The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA)

Lauren E. Connor; Amit Delori; Ian B. Hutchison; Niamh Nic Daeid; Oliver B. Sutcliffe; Iain D. H. Oswald

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The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA)

机译：狂喜和痛苦; 3,4-亚甲二氧基甲基苯丙胺（MDMA）的压缩研究

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MDMA (3,4-methylenedioxymethamphetamine) is a Class A substance that is usually found in a tableted form. It is only observed in one orthorhombic polymorph under ambient conditions. It shows slight positional disorder around the methlyenedioxy ring which persists during compression up to 6.66 GPa. The crystal quality deteriorates above 6.66 GPa where the hydrostatic limit of the pressure-transmitting medium is exceeded. The structure undergoes anisotropic compression with the a-axis compressing the greatest (12% cf. 4 and 10% for the b- and c-axes, respectively). This is due to the pattern of the hydrogen bonding which acts like a spring and allows the compression along this direction.

机译：MDMA（3,4-亚甲基二氧基甲基苯丙胺）是通常以片剂形式发现的A类物质。仅在环境条件下以一种正交晶型观察到。它在甲二烯二氧基环周围显示出轻微的位置紊乱，在压缩至6.66 GPa的过程中持续存在。在超过6.66 GPa的情况下，晶体质量恶化，超过了压力传输介质的静水极限。该结构受到各向异性压缩，其中a轴压缩最大（b轴和c轴分别为12％和4％和10％）。这是由于氢键的作用方式像弹簧一样，并允许沿该方向压缩。

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《Acta Crystallographica, Section B. Structural science, crystal engineering and materials》 |2015年第1期|共7页
作者
Lauren E. Connor; Amit Delori; Ian B. Hutchison; Niamh Nic Daeid; Oliver B. Sutcliffe; Iain D. H. Oswald;
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正文语种 eng
中图分类晶体学;
关键词
ecstasy; agony; compression;

机译：摇头丸;痛苦;压缩;

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1. The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA) [J] . Lauren E. Connor, Amit Delori, Ian B. Hutchison, Acta Crystallographica, Section B. Structural science, crystal engineering and materials . 2015,第1期

机译：狂喜和痛苦; 3,4-亚甲二氧基甲基苯丙胺（MDMA）的压缩研究
2. An ab initio study on 3,4-methylenedioxymethamphetamine, MDMA (ecstasy) and its derivatives [J] . Zahra Fallah Ebrahimi International journal of computational biology and drug design . 2016,第2期

机译：从头开始研究3,4-亚甲基二氧基甲基苯丙胺，摇头丸（摇头丸）及其衍生物
3. An ab initio study on 3,4-methylenedioxymethamphetamine, MDMA (ecstasy) and its derivatives [J] . Zahra Fallah Ebrahimi International journal of computational biology and drug design . 2016,第1期

机译：从头开始研究3,4-亚甲基二氧基甲基苯丙胺，摇头丸（摇头丸）及其衍生物
4. A cycle of online education ecstasy/agony: To MOOC or not to MOOC [C] . Tu Chih-Hsiung, McIsaac Marina, Doyle Robert, 2013 IEEE 63rd Annual Conference International Council for Educational Media : we Learning: Content, Community and Collaboration . 2013

机译：在线教育狂喜/狂热的周期：是否接受MOOC
5. Neuropharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") and its stereoisomers. [D] . Murnane, Kevin Sean. 2010

机译：3，4-亚甲基二氧基甲基苯丙胺（MDMA，“摇头丸”）及其立体异构体的神经药理学。
6. Urinary Excretion Kinetics of 34-Methylenedioxymethamphetamine (MDMA Ecstasy) and Its Phase I and Phase II Metabolites in Humans following Controlled MDMA Administration [O] . Andrea E. Schwaninger, Markus R. Meyer, Allan J. Barnes, -1

机译：在人类34-亚甲基二氧甲基苯丙胺（mDma摇头丸）及I期和II期代谢产物的排泄尿动力学控制以下mDma管理
7. The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA) [O] . Connor, L. E., Delori, A., Hutchison, I. B., 2015

机译：狂喜和痛苦； 3,4-亚甲二氧基甲基苯丙胺（MDMA）的压缩研究
8. Mapping Toxicant-Induced Nervous System Damage with a Cupric Silver Stain: AQuantitative Analysis of Neural Degeneration Induced by 3,4-Methylenedioxymethamphetamine (MDMA) (Revised) [R] . Jensen, K. F. 1992

机译：用铜银染色法绘制毒物诱导的神经系统损伤：3,4-亚甲二氧基甲基苯丙胺（mDma）诱导的神经变性的定量分析（修订版）

The ecstasy and the agony; compression studies of 3,4-methylenedioxymethamphetamine (MDMA)

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