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首页> 外文期刊>Biocybernetics and biomedical engineering >Numerical simulations of the pulsatile blood flow in the different types of arterial fenestrations: Comparable analysis of multiple vascular geometries
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Numerical simulations of the pulsatile blood flow in the different types of arterial fenestrations: Comparable analysis of multiple vascular geometries

机译：不同类型动脉衰落中脉动血流的数值模拟：多血管几何形状的可比分析

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In medical terms, fenestration stands for an anomaly within the circulatory system in which the blood vessel lumen is divided into two separate channels that rejoin in the distal part of this vessel. The primary objective of this research was to analyze the impact of the left vertebral artery (LVA) and basilar artery (BA) fenestrations on the blood flow characteristics in their regions and downstream, in the cerebral circulation. The geometrical data, obtained from the angio-Computed Tomography, were the basis for the generation of a 3D model in SolidWorks 2015. In order to observe the flow characteristics within the whole spatial domain, computational fluid dynamics was involved in performing simulations of the blood flow in the patient-specific arterial system (beginning with the aortic arch and finishing with the Circle of Willis). To examine the flow distribution changes resulting from altered fenestration geometries, additional models were built. The blood flow velocity, volume flow rate and shear stress distribution were analyzed within this study. It was proven that the length/size/ position of the fenestration altered the flow characteristics in different manners. The investigations showed that the patient-specific LVA, at the V3 section (extracranial part of the artery located between the spine and the skull), is not a reason of aneurysm formation. However, BA fenestration at the proximal segment might be a possible reason of future aneurysm formation. It was proven that the computational fluid dynamics tool could support medical diagnostic procedures and multivessel brain vascular disease treatment planning. (C) 2018 The Authors. Published by Elsevier B.V. on behalf of Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences.
机译：在医学方面，更eneStration代表在循环系统内的异常，其中血管腔被分成两个单独的通道，该通道在该容器的远端部分中重新加入。本研究的主要目的是分析左椎动脉（LVA）和基底动脉（BA）衰落对脑循环中的血流特征对血流特征的影响。从血管计算的层析成像获得的几何数据是SolidWorks 2015中的3D模型的产生的基础。为了观察整个空间域内的流动特性，计算流体动力学涉及进行血液的模拟在特定患者特异性动脉系统中流动（从主动脉弓开始，用威利斯圈完成）。要检查由更改的更改变更几何形状产生的流量分布变化，建立了其他模型。在该研究中分析了血流速度，体积流量和剪切应力分布。据证明，衰变的长度/尺寸/位置以不同的方式改变了流动特征。研究表明，患者特异性LVA，在V3段（位于脊柱和颅骨之间的动脉的颅骨部分），不是动脉瘤形成的原因。然而，近端段的BA FeneStration可能是未来动脉瘤形成的可能原因。据证明，计算流体动力学工具可以支持医学诊断程序和多血糖脑血管疾病治疗计划。 （c）2018作者。由elsevier b.v出版。代表纳雷斯州博士科学学院的波兰科学院生物医学工程。

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