...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Acta Cytologica: The Journal of Clinical Cytology and Cytopathology >The role of urine cytology for 'decoy cells' as a screening tool in renal transplant recipients
【24h】

The role of urine cytology for 'decoy cells' as a screening tool in renal transplant recipients

机译：尿液细胞学对“诱饵细胞”作为肾移植受者筛查工具的作用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective: To determine the role of urine cytology for 'decoy cells' as a screening tool for polyomavirus type BK (BKV) infection in renal transplant recipients. Study Design: This was a prospective cohort study of patients undergoing renal transplantation between 2006 and 2010. Results: A total of 442 patients underwent urine cytology for decoy cells, 27.8% underwent 1 examination only and 72.2% more than one. Of the 1,713 examinations reviewed, 426 (24.9%) were positive and 785 (45.8%) were negative for 'decoy' cells, 380 (22.2%) showed degenerated tubular cells and 122 (7.1%) were unsatisfactory for analysis. Urine cytology was found to have a specificity of 68.5%, a sensitivity of 84.6%, a positive predictive value of 21.2%, a negative predictive value of 97.8% and an overall accuracy of 69.9%. The incidence of polyomavirus nephropathy among the patients investigated was 11.8%. Of the 442 patients, 32 (7.2%) had graft loss, which was attributed to BKV nephropathy in 2 (6.2% of the 32). Conclusions: Urine cytology is an effective screening method for monitoring renal transplant patients, with high sensitivity and a high negative predictive value, and can therefore be used routinely in the follow-up of renal transplant patients.
机译：目的：确定尿液细胞学在“诱饵细胞”中作为肾移植受者多瘤病毒BK型感染的筛查工具的作用。研究设计：这是一项对2006年至2010年间接受肾移植的患者进行的前瞻性队列研究。结果：共有442例接受了诱饵细胞尿液细胞学检查的患者，其中27.8％仅接受了一次检查，而多于72.2％。在审查的1,713项检查中，“诱饵”细胞阳性426例（24.9％），阴性785例（45.8％），退化的肾小管细胞380例（22.2％），分析不满意，有122例（7.1％）。尿液细胞学检查的特异性为68.5％，敏感性为84.6％，阳性预测值为21.2％，阴性预测值为97.8％，总准确度为69.9％。在所调查的患者中，多瘤病毒肾病的发生率为11.8％。在这442例患者中，有32例（7.2％）发生了移植物丢失，这归因于2例（32例中的6.2％）的BKV肾病。结论：尿液细胞学检查是监测肾移植患者的有效方法，具有较高的敏感性和较高的阴性预测价值，因此可常规用于肾移植患者的随访。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号