...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>British Journal of Haematology >Relationships among lymphocyte subsets, cytokines, and the pulmonary inflammation index in coronavirus (COVID‐19) infected patients
【24h】

Relationships among lymphocyte subsets, cytokines, and the pulmonary inflammation index in coronavirus (COVID‐19) infected patients

机译：淋巴细胞亚群，细胞因子和冠状病毒（Covid-19）感染患者肺炎症的关系

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Summary We explored the relationships between lymphocyte subsets, cytokines, pulmonary inflammation index (PII) and disease evolution in patients with (corona virus disease 2019) COVID‐19. A total of 123 patients with COVID‐19 were divided into mild and severe groups. Lymphocyte subsets and cytokines were detected on the first day of hospital admission and lung computed tomography results were quantified by PII. Difference analysis and correlation analysis were performed on the two groups. A total of 102 mild and 21 severe patients were included in the analysis. There were significant differences in cluster of differentiation 4 (CD4 + T), cluster of differentiation 8 (CD8 + T), interleukin 6 (IL‐6), interleukin 10 (IL‐10) and PII between the two groups. There were significant positive correlations between CD4 + T and CD8 + T, IL‐6 and IL‐10 in the mild group ( r 2 ?=?0·694, r 2 ?=?0·633, respectively; P ??0·01). After ‘five‐in‐one’ treatment, all patients were discharged with the exception of the four who died. Higher survival rates occurred in the mild group and in those with IL‐6 within normal values. CD4 + T, CD8 + T, IL‐6, IL‐10 and PII can be used as indicators of disease evolution, and the PII can be used as an independent indicator for disease progression of COVID‐19.
机译：发明内容我们探讨了淋巴细胞亚群，细胞因子，肺炎炎症指数（PII）和疾病演进的关系（电晕病毒疾病2019）Covid-19。共有123例Covid-19患者分为轻度和严重的群体。在医院入院的第一天检测到淋巴细胞亚群和细胞因子，并通过PII量化肺计算断层扫描结果。对两组进行差异分析和相关分析。分析中共有102例轻度和21例严重患者。分化4（CD4 + T），分化8（CD8 + T），白细胞介素6（IL-6），白细胞介素10（IL-10）和PII之间存在显着差异，两组之间。在轻度基团中的CD4 + T和CD8 + T，IL-6和IL-10之间存在显着的正相关（R 2？= 0·694，R 2？= 0·633分别; P？ ？0·01）。在“五一”治疗后，所有患者都出院，除了四个死亡的人。在温和的组中发生较高的存活率，并在正常值内与IL-6的存活率发生。 CD4 + T，CD8 + T，IL-6，IL-10和PII可用作疾病演化的指标，PII可用作Covid-19的疾病进展的独立指标。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号