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首页> 外文期刊>Burns: Including Thermal Injury >Artificial dermal templates: A comparative study of NovoSorb (TM) Biodegradable Temporising Matrix (BTM) and Integra (R) Dermal Regeneration Template (DRT)
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Artificial dermal templates: A comparative study of NovoSorb (TM) Biodegradable Temporising Matrix (BTM) and Integra (R) Dermal Regeneration Template (DRT)

机译:人造皮肤模板:Novosorb(TM)可生物降解颞育矩阵(BTM)和Integra(R)皮肤再生模板(DRT)的对比研究

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摘要

Background: Artificial dermal templates play an important role in physiologic wound closure after injury. In addition to contributing to stable, durable and flexible wound closure, they provide a scaffold for tissue repair. Several dermal templates are commercially available, with animal-derived Integra (R) dermal regeneration template perhaps the most widely used. NovoSorb (TM) Biodegradable Temporising Matrix (BTM) is a fully synthetic alternative that eliminates any risk of cross-species residual antigenicity. In this study, we aimed to compare early response after application of NovoSorb (TM) BTM with Integra (R) in terms of temporary wound closure, host cell infiltration, neovascularisation and collagen deposition in a mouse model.
机译:背景:人造皮肤模板在损伤后在生理伤口闭合中发挥着重要作用。 除了有助于稳定,耐用且柔性伤口闭合外,它们还为组织修复提供了支架。 几种真皮模板可商购获得,具有动物衍生的细菌(R)皮肤再生模板,也许最广泛使用。 Novosorb(TM)可生物降解的休闲基质(BTM)是一种完全合成的替代方案,可消除跨物种残留抗原性的任何风险。 在这项研究中,我们旨在在临时伤口闭合,宿主细胞浸润,新生血管和胶原沉积在小鼠模型中施用Novosorb(TM)BTM后的早期反应。

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