Fatty Acid Desaturation Gets a NAD(+) Reputation

Lutkewitte Andrew J.; Burgess Shawn C.; Finck Brian N.

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Fatty Acid Desaturation Gets a NAD(+) Reputation

机译：脂肪酸去饱和度得多了（+）声誉

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delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD(+) by this desaturase reaction is an adaptive response to NAD(+) depletion that may regulate cellular REDOX status.

机译：Delta-5去饱和酶和Delta-6去饱和酶是已知参与高度不饱和脂肪酸的合成酶的酶。在这个问题中，Kim等人。（2019）显示该去饱和酶反应的NAD（+）的产生是对NAD（+）耗竭的适应性反应，其可调节细胞氧化还原状态。

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《Cell metabolism》 |2019年第4期|共3页
作者
Lutkewitte Andrew J.; Burgess Shawn C.; Finck Brian N.;
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作者单位

Washington Univ Sch Med Dept Med Div Geriatr &

Nutr Sci Ctr Human Nutr St Louis MO 63110 USA;

Univ Texas Southwestern Med Ctr Dallas Ctr Human Nutr Dept Pharmacol Dallas TX USA;

Washington Univ Sch Med Dept Med Div Geriatr &

Nutr Sci Ctr Human Nutr St Louis MO 63110 USA;

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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. Fatty Acid Desaturation Gets a NAD(+) Reputation [J] . Lutkewitte Andrew J., Burgess Shawn C., Finck Brian N. Cell metabolism . 2019,第4期

机译：脂肪酸去饱和度得多了（+）声誉
2. De novo synthesis and desaturation of fatty acids at the mitochondrial acyl‐carrier protein, a subunit of NADH:ubiquinone oxidoreductase in Neurospora crassa [J] . Husmann Heribert, Peine Thorsten, Schneider Regina, FEBS Letters . 1992,第2期

机译：线粒体酰基载体蛋白的脂肪酸从头合成和去饱和，NADH的亚单位：泛醌氧化还原酶
3. Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD(+) Recycling [J] . Kim Wondong, Deik Amy, Gonzalez Clicerio, Cell metabolism . 2019,第4期

机译：多不饱和脂肪酸去饱和是甘油酵母和（+）回收的机制
4. Cyclopropenyl Fatty Acids (Baobab Seed Oil)Feeding Inhibits Rat Liver Fatty Acid Desaturation [C] . J-M.Cao.J.Bezard, J.P.Blond '94 International Symposium amp; Exhibition on New Approaches in the Production of Food Stuffs and Intermediate Products From Cereal Grains and Oil Seeds 16-19 November 1994 Beijing, China . 1994

机译：环丙烯基脂肪酸（猴面包树籽油）的进食抑制大鼠肝脏脂肪酸的去饱和
5. Functional genomics of Theobroma cacao fatty acid biosynthesis: Convergence of fatty acid desaturation, embryo development, and defense signaling responses. [D] . Zhang, Yufan. 2014

机译：可可豆脂肪酸生物合成的功能基因组学：脂肪酸去饱和，胚胎发育和防御信号响应的收敛。
6. Threonine 286 of fatty acid desaturase 7 is essential for ω-3 fatty acid desaturation in the green microalga Chlamydomonas reinhardtii [O] . Jong-Min Lim, Jayaraman Vikramathithan, Kwon Hwangbo, 2020

机译：脂肪酸去饱和酶7的苏氨酸286对绿色微藻衣藻（Chlamydomonas reinhardtii）中ω-3脂肪酸去饱和至关重要
7. De novo synthesis and desaturation of fatty acids at the mitochondrial acyl-carrier protein, a subunit of NADH:ubiquinone oxidoreductase in Neurospora crassa [O] . Zensen Ralf, Husmann Heribert, Schneider Regina, 1992

机译：线粒体酰基载体蛋白（NADH：泛醌氧化还原酶的亚单位）中线粒体酰基载体蛋白的脂肪酸从头合成和去饱和
8. Synthesis and Biological Evaluation of (E)-19-Iodo-3,3-Dimethyl-18-Nonadecenoic Acid, a New Dimethyl-Branched Long-Chain Fatty Acid to Evaluate Regional Myocardial Fatty Acid Uptake [R] . Goodman, M. M., Ambrose, K. R., Neff, K. H., 1986

机译：（E）-19-碘-3,3-二甲基-18-十一碳烯酸（一种新的二甲基支链长链脂肪酸）的合成和生物学评价，用于评估局部心肌脂肪酸的摄取

Fatty Acid Desaturation Gets a NAD(+) Reputation

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