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Quadriceps-strengthening exercise and quadriceps and knee biomechanics during walking in knee osteoarthritis: A two-centre randomized controlled trial

机译:在膝关节骨关节炎行走期间,Quadriceps-强化运动和脚腹肌和膝肿瘤生物力学:一个双中心随机对照试验

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ObjectiveTo assess the effect of quadriceps strengthening on quadriceps muscle force, power, and work and tibio-femoral compressive loads during walking in adults with knee osteoarthritis. MethodsStudy design: Two-center, randomized, controlled trial.Intervention: Patients with knee osteoarthritis were randomly allocated to quadriceps strengthening program (3 times weekly) or no attention control group.Main outcome measures: Primary outcome was change from baseline in peak quadriceps force during walking at 12?weeks. Secondary outcomes included quadriceps power and work, knee compression forces during walking estimated with musculoskeletal modeling, muscle strength and pain and function. Outcomes were measured at baseline and 12?weeks. Results30 patients were randomized to receive either training (n?=?15) or no attention (n?=?15). At follow-up, there were no statistical differences between groups for maximum quadriceps force, quadriceps positive power, negative work, and positive work, and knee compressive force. Maximum negative quadriceps power in early stance was statistically significantly increased 36% in the training group compared to the control group which was most likely partially a response to faster walking velocity at follow-up. Muscle strength and patient reported pain and function were improved in the training group compared to the control group. ConclusionsQuadriceps strength training leads to increased muscle strength and improved symptomatic and functional outcomes but does not change quadriceps or knee joint biomechanics during walking. The biomechanical mechanism of improved health with strength training in knee osteoarthritis patients remains unknown.ClinicalTrials.gov Identifier:NCT01538407.
机译:ObjectiveTo评估Quadriceps加强对膝关节骨关节炎的成人行走期间Quaddriceps肌肉力量,动力和工作和胫骨压缩载荷的影响。方法设计:双中心,随机,受控试验。治疗:膝关节骨关节炎的患者被随机分配给Quaddriceps加强计划(每周3次)或没有注意力控制组。当然措施在12岁时行走期间。二次结果包括Quaddriceps电力和工作,膝关节压缩力在步​​行期间估计肌肉骨骼建模,肌肉力量和疼痛和功能。结果是在基线和12个周的基线测量的。结果30患者随机接受训练(N?=?15)或不关注(n?=?15)。在随访时,群体之间没有统计差异,用于最大Quadriceps力,Quaddriceps正极功率,负面工作和积​​极的工作以及膝关节压缩力。与对照组相比,早期立场的最大负Quadriceps电力在训练组中统计上显着增加了36%,这是对对照组最有可能部分响应随访时更快的行走速度的反应。与对照组相比,肌肉力量和患者报告训练组的疼痛和功能得到改善。结论Quadriceps力量训练导致肌肉力量增加和改善的症状和功能性结果,但在行走期间不会改变Quadriceps或膝关节生物力学。膝关节骨关节炎患者强度训练改善健康的生物力学机制仍然不明未知.ClinicalTrials.gov标识符:NCT01538407。

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