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首页> 外文期刊>Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) >Peri-ictal Prone Position Is Associated With Independent Risk Factors For Sudden Unexpected Death In Epilepsy: A Controlled Video-EEG Monitoring Unit Study
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Peri-ictal Prone Position Is Associated With Independent Risk Factors For Sudden Unexpected Death In Epilepsy: A Controlled Video-EEG Monitoring Unit Study

机译：Peri-ictal Pronal位置与癫痫突然意外死亡的独立危险因素有关：受控视频EEG监测单元研究

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Introduction. Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in patients with chronic drug-resistant epilepsy, and peri-ictal prone position has been elucidated as a risk factor for SUDEP. We aimed to investigate consecutive patients in peri-ictal prone positions in our video EEG monitoring (VEM) unit and compare patients with and without peri-ictal prone position to emphasize its relationship with other independent risk factors for SUDEP. Methods. We retrospectively screened all patients with peri-ictal prone position who underwent VEM for a 10-year period and these patients constituted the prone (+) group. All patients without peri-ictal prone position who underwent VEM in the past 2 years constituted the prone (-) control group. Sequences of peri-ictal positions and interventions were evaluated. Clinical and laboratory features and SUDEP-7 scores were compared between the groups. Results. A total of 21 seizures were identified with peri-ictal prone position from 16 patients. SUDEP-7 scores were significantly higher in the prone (+) group. Longer duration of epilepsy, early age at seizure onset, mental retardation, and frequency of seizures of any type (50 seizures per month for the past year) were found significantly different between the prone (+) and prone (-) groups. Conclusion. Peri-ictal prone position in the VEM unit may relate with other independent risk factors of SUDEP, especially with mental retardation. Nocturnal supervision becomes important to reduce SUDEP risk, especially in patients with mental retardation.
机译：介绍。癫痫患者突然意外死亡（SUDEP）是慢性耐药癫痫患者死亡的主要原因，并且PERI-ICTAL PRONE位置被阐明为sudep的危险因素。我们旨在调查我们的视频EEG监测（VEM）单位的Peri-ICTAL俯卧位的连续患者，并比较有和没有Peri-ICTAL Pronal职位的患者，强调其与Sudep的其他独立风险因素的关系。方法。我们回顾性地筛选了所有患有vem的Peri-ICTAL俯卧位患者，该患者在10年期间接受了vem，这些患者构成了易于（+）组。所有没有Peri-ICTAL Pronal Prone的患者在过去2年中接受了vem的突破，构成了Prone（ - ）对照组。评估了肝癌的序列和干预措施。在组之间比较临床和实验室特征和Sudep-7分数。结果。总共21例癫痫发作，从16名患者均有突出的遗传症。易于（+）组的Sudep-7分数显着高。癫痫患者持续时间较长，癫痫发作发生的早期性，发育迟滞和任何类型的癫痫发作的次数（过去一年每月缉获的次数）在显着差异，易于（+）和易于（ - ）组之间显着差异。结论。 VEM单元中的PERI-ICTAL俯卧位可能与SUDEP的其他自动危险因素有关，特别是精神发育迟滞。夜间监督对于减少sudep风险，特别是在精神发育迟滞的患者中都很重要。

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