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Reevaluation of the Critically Ill Patients With Nonconvulsive Status Epilepticus by Using Salzburg Consensus Criteria

机译:使用萨尔茨堡共识标准重新评估患有非盲目状态癫痫的患者

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Objective. We aimed to assess the usefulness of the Salzburg Consensus Criteria (SCC) for determining the prognosis of critically ill patients with nonconvulsive status epilepticus (NCSE). Methods. We retrospectively reviewed consecutive patients with unconsciousness followed up in the intensive care unit (ICU). Three clinical neurophysiologists, one of them blinded to clinical and laboratory data, reevaluated all EEG data independently and determined NCSE according to SCC. The incidence of NCSE and ictal EEG patterns and their relationship to clinical, laboratory, neuroradiological, and prognostic findings were assessed. Results. A total of 107 consecutive patients with mean age 68.2 +/- 15.3 years (57 females) were enrolled in the study. Primary neuronal injury was detected in 59 patients (55.7%). Thirty-three patients (30.8%) were diagnosed as NCSE. While authors decided to treat 33 patients (30.8%), 32 patients (29.9%) had been treated in real-life evaluation. Clinical and EEG improvement were detected in 12 patients (11.3%) in real-life treatment group showing correlation with lack of intubation and ICU stay related to postsurgical event. Rate of mortality (45.8%) was high showing association with systemic-metabolic etiology, severity of coma and presence of plus modifiers in the EEG. Conclusion and Significance. Our findings suggest that SCC is highly compatible with clinical practice in the decision for treatment of patients with NCSE. The presence of plus modifiers in the EEG was found to be associated with mortality in these patients and was a significant marker for the high mortality rate.
机译:客观的。我们的旨在评估萨尔茨堡共识标准(SCC)的有用性,用于确定患有非盲目状态癫痫病毒(NCSE)的关键病患者的预后。方法。我们回顾性地审查了连续的无意识患者,随后在重症监护室(ICU)。三个临床神经生理学家,其中一个蒙蔽了临床和实验室数据,根据SCC独立重新评估所有脑电图数据并确定NCSE。评估NCSE和ICTAL eEG模式的发病率及其与临床,实验室,神经加理学和预后发现的关系。结果。共有107名连续年龄为68.2 +/- 15.3岁(57名女性)的患者参加了该研究。在59名患者中检测到原发性神经元损伤(55.7%)。诊断为NCSE的33名患者(30.8%)。虽然作者决定治疗33名患者(30.8%),但在现实生活评估中治疗了32名患者(29.9%)。在12名患者(11.3%)中检测到临床和脑电图改进,现实治疗组显示与缺乏插管和ICU与后勤事件相关的相关性。死亡率(45.8%)呈高显示与全身代谢病因,昏迷的严重程度和脑电图中的加质调节剂的关联。结论与意义。我们的研究结果表明,SCC与临床实践高度相容,在决定NCSE患者的决定中。发现脑电图中的加质剂的存在与这些患者的死亡率有关,并且对于高死亡率是一个重要的标志物。

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