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Exclusion of overlapping symptoms in DSM-5 mixed features specifier: heuristic diagnostic and treatment implications

机译:排除DSM-5混合特征规定的重叠症状:启发式诊断和治疗意义

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This article focuses on the controversial decision to exclude the overlapping symptoms of distractibility, irritability, and psychomotor agitation (DIP) with the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM- 5) mixed features specifier. In order to understand the placement of mixed states within the current classification system, we first review the evolution of mixed states. Then, using Kraepelin's original classification of mixed states, we compare and contrast his conceptualization with modern day definitions. The DSM- 5 workgroup excluded DIP symptoms, arguing that they lack the ability to differentiate between manic and depressive states; however, accumulating evidence suggests that DIP symptoms may be core features of mixed states. We suggest a return to a Kraepelinian approach to classification-with mood, ideation, and activity as key axes-and reintegration of DIP symptoms as features that are expressed across presentations. An inclusive definition of mixed states is urgently needed to resolve confusion in clinical practice and to redirect future research efforts.
机译:本文重点介绍,以引入精神障碍的诊断和统计手册,第五版(DSM-5)混合特征说明符引入争议的决定,以排除分散症状,烦躁和精神多症(DIP)的重复决定。为了了解当前分类系统内混合状态的放置,我们首先审查了混合状态的演变。然后,使用Kraepelin的混合状态分类,我们与现代定义进行比较和对比他的概念化。 DSM-5工作组排除了DIP症状,争论他们缺乏区分躁狂和抑郁状态的能力;然而,累积证据表明DIP症状可能是混合状态的核心特征。我们建议恢复kraepelinian的分类方法,以与情绪,观念和活动作为关键轴和作为横跨演示表达的功能的重新融入症状。迫切需要在临床实践中解决混乱状态的包容性定义,并重新利用未来的研究工作。

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