Point-of-Care Testing of Troponin Levels Compared With Automated Laboratory Evaluation A Reliability Study

Adacilis Ramirez Sardi; Julie A. Lamoureux; Tanya M. Cohn; Shirley G. Phillip-Samuel

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Point-of-Care Testing of Troponin Levels Compared With Automated Laboratory Evaluation A Reliability Study

机译：与自动化实验室评估相比，肌钙蛋白水平的护理点测试可靠性研究

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Traditionally, troponin levels are measured in the blood using an automated laboratory protocol, but the use of a faster technology, the point-of-care (POC) testing of troponin levels, has shown promise in the effective differential diagnosis of cardiac injury. The purpose of this study was to compare the 2 methods. A total of 1567 patients were seen in the emergency department who were tested with both the POC iSTAT troponin and laboratory troponin from a secondary analysis of retrospective data collected between June 2012 and December 2012. The values for laboratory troponin varied between 0 and 30 with a mean and standard deviation of 0.060 ± 0.842 and the values for POC testing varied between 0 and 17.2 with a mean and standard deviation of 0.042 ± 0.492. The Bland-Altman analysis showed a systematic negative bias for the POC values compared with the laboratory troponin values. Lowering the POC cut-off value for troponin to 0.035 yielded 3 out of 4 better validity coefficients compared with those with the suggested manufacturer's cut-off value of 0.08 when predicting the gold standard. The POC troponin can be used to measure troponin level and similar diagnosis if the cut-off value for the POC troponin is lowered to 0.035 instead of the 0.08 suggested manufacturer's cut-off.

机译：传统上，使用自动化实验室方案在血液中测量肌钙蛋白水平，但使用更快的技术，肌钙蛋白水平的护理点（PoC）测试，在心脏损伤的有效鉴别诊断中表明了承诺。本研究的目的是比较2种方法。在2012年6月至2012年6月期间收集的回顾性数据的二级分析中，急诊部门在急诊部门中看到了1567名患者。实验室肌钙蛋白的价值在0到30之间的次要分析。平均值和标准偏差为0.060±0.842，PoC测试的值在0和17.2之间变化，平均值和标准偏差为0.042±0.492。与实验室肌钙蛋白值相比，Bland-Altman分析显示了PoC值的系统负偏见。降低肌钙蛋白的POC截止值为0.035，而在预测黄金标准时，建议制造商的截止值为0.08的较好的有效系数，产生了3个。如果POC肌钙蛋白的截止值降至0.035，而不是0.08建议制造商的截止，则PoC肌钙蛋白可用于测量肌钙蛋白水平和类似的诊断。

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来源
《Critical care nursing quarterly》 |2016年第4期|共7页
作者
Adacilis Ramirez Sardi; Julie A. Lamoureux; Tanya M. Cohn; Shirley G. Phillip-Samuel;
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作者单位

West Kendall Baptist Hospital Miami Florida;

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原文格式 PDF
正文语种 eng
中图分类护理学;
关键词
myocardial infarction; point-of-care; sensitivity; specificity; troponin;

机译：心肌梗死;护理点;敏感性;特异性;肌钙蛋白;

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1. Point-of-Care Testing of Troponin Levels Compared With Automated Laboratory Evaluation A Reliability Study [J] . Adacilis Ramirez Sardi, Julie A. Lamoureux, Tanya M. Cohn, Critical care nursing quarterly . 2016,第4期

机译：与自动化实验室评估相比，肌钙蛋白水平的护理点测试可靠性研究
2. Consequences of high-sensitivity troponin T testing applied in a primary care population with chest pain compared with a commercially available point-of-care troponin T analysis: an observational prospective study [J] . Per O Andersson, Jan-Erik Karlsson, Eva Landberg, BMC research notes . 2015,第1期

机译：高敏感性肌钙蛋白T检测适用于患有胸痛的初级保健人群与市售即时护理肌钙蛋白T分析相比的观察性前瞻性研究
3. Performance Evaluation of Cardiac Troponin I Assay: A Comparison Between the Point-of-care Testing Radiometer AQT90 FLEX and the Central Laboratory Siemens Advia Centaur Analyzer [J] . Sibtain Ahmed, Lena Jafri, Ahmed Raheem, Cureus. . 2019,第3期

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6. Consequences of high-sensitivity troponin T testing applied in a primary care population with chest pain compared with a commercially available point-of-care troponin T analysis: an observational prospective study [O] . Per O Andersson, Jan-Erik Karlsson, Eva Landberg, 2015

机译：与市售的即时护理性肌钙蛋白T分析相比对患有胸痛的初级保健人群进行高敏感性肌钙蛋白T检测的结果：一项观察性前瞻性研究
7. Consequences of high-sensitivity troponin T testing applied in a primary care population with chest pain compared with a commercially available point-of-care troponin T analysis : an observational prospective study [O] . Andersson, Per, Karlsson, Jan-Erik, Landberg, Eva, 2015

机译：高敏感性肌钙蛋白T检测适用于患有胸痛的初级保健人群与市售的即时护理肌钙蛋白T分析相比的观察性前瞻性研究

Point-of-Care Testing of Troponin Levels Compared With Automated Laboratory Evaluation A Reliability Study

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