Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia

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Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia

机译：ondansetron在全身麻醉下对阿片类药物上瘾患者的戒断症，芬太尼要求和疼痛缓解的影响

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Background: Serotonin 5-HT3 receptor antagonists such as ondansetron have been investigated to attenuate opioid withdrawal signs in studies. Objective: Therefore, we designed a randomized double-blinded placebo-controlled trial to evaluate this effect on opioid-addicted patients who were admitted to the orthopedic department for surgery due to bone fractures.

机译：背景：已经研究了血清素5-HT3受体拮抗剂，例如ondansetron，以减轻研究中的阿片类药物戒断。目的：因此，我们设计了随机的双盲安慰剂对照试验，以评估因骨折而被录取的阿片类药物上瘾患者的效果。

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《Current clinical pharmacology》 |2019年第3期|共10页
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正文语种 eng
中图分类药学;
关键词
Serotonin receptors; anesthesiology; antiemetic drugs; abuse; pain; dislocations;

机译：血清素受体;麻醉学;止吐药;滥用;疼痛;脱臼;

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1. Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia [J] . Current clinical pharmacology . 2019,第3期

机译：ondansetron在全身麻醉下对阿片类药物上瘾患者的戒断症，芬太尼要求和疼痛缓解的影响
2. PAIN RELIEF: Is this patient in pain or seeking a fentanyl fix? [J] . Dennis Edgerly JEMS : . 2016,第11期

机译：疼痛缓解：这个患者是否疼痛或寻求芬太尼统一？
3. A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioid-tolerant patients with noncancer-related chronic pain. [J] . Farrar JT, Messina J, Xie F, Pain medicine : . 2010,第9期

机译：一项为期12周的新颖研究，包括三个随机，双盲安慰剂对照期，用于评估芬太尼颊片对阿片耐受性非癌相关性慢性疼痛患者的突破性疼痛的缓解作用。
4. Usefulness of a Fentanyl Patch (Durotep~(TM)) and Conversion Rates Achieved When Switched from Morphine Preparations or Other Analgesics on Cancer Pain Patients [C] . Y. Akiyama, M. Iseki, Y. Tani, International Pain Clinic . 2004

机译：芬太尼贴剂（Durotep〜（TM））和转换率，当从吗啡制剂或其他镇痛药转换为癌症疼痛患者时达到的转化率
5. Opioid withdrawal signs and symptoms in the pediatric patient during opioid tapering. [D] . Fisher, Deborah. 2012

机译：阿片类药物逐渐减量的小儿阿片类药物戒断症状和体征。
6. Does transdermal fentanyl work in patients with low BMI? Patient‐reported outcomes of pain and percent pain relief in cancer patients on transdermal fentanyl [O] . Natalie Moryl, Ali Bokhari, Yvona Griffo, 2019

机译：BMI较低的患者是否可以使用透皮芬太尼？病人通过透皮芬太尼报告的疼痛结局和疼痛缓解百分比
7. Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia [O] . Farzaneh Mahikhan, Morteza Hashemian, Tania Dehesh, 2019

机译：在全身麻醉下，ondansetron对阿片类药物上瘾患者的戒断症，芬太尼要求和疼痛缓解的影响

Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia

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