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Fish oil supplementation and maintaining muscle mass in chronic disease: state of the evidence

机译：鱼油补充和维持慢性疾病肌肉肿块：证据状态

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摘要

Purpose of review Providing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in the form of fish oils, to benefit muscle is an emerging area of interest. The aim of this work was to evaluate the current literature that has assessed muscle mass as an outcome during a fish oil intervention in any chronic disease. Recent findings The vast majority of studies published in the last 3 years (12 of 15) have been conducted in the oncological setting, in patients undergoing treatment for cancers of the gastrointestinal tract, breast, head and neck, lung, cervix, and hematological cancers. Three studies were conducted in patients with chronic obstructive pulmonary disease (COPD). Fish oil was provided as part of nutrient mixtures in 12 studies and as capsules in three studies. Overall, the evidence for an effect of fish oil supplementation on muscle mass in patients with cancer undergoing treatment and in COPD remains unequivocal and reveals limited new knowledge in the area of fish oil supplementation in the cancer setting. Recent literature continues to provide mixed evidence on the efficacy of fish oil on muscle mass and function. The present review highlights challenges in comparing and interpreting current studies aimed at testing fish oil supplementation for muscle health.
机译：审查提供eicosapentaeno的酸（EPA）和DoCosahexeno酸（DHA），以鱼油的形式提供益处肌肉是一种新兴的兴趣领域。这项工作的目的是评估当前的文献，这些文献在任何慢性疾病中都会评估肌肉质量作为病毒干预的结果。最近的发现，在肿瘤患者中，在肿瘤患者中进行了过去3年（第12条第12条）的绝大多数研究，以治疗胃肠道，乳腺癌，头部和颈部，肺癌，血管学癌症癌症。在慢性阻塞性肺疾病（COPD）患者中进行了三项研究。将鱼油作为12项研究中的营养混合物的一部分提供提供，并在三项研究中作为胶囊。总体而言，癌症患者和COPD患者肌肉肿块效果的证据仍然明确，并揭示了癌症环境中鱼油补充领域的有限新知识。最近的文献继续提供关于鱼油对肌肉质量和功能的功效的混合证据。本综述突出了比较和解释目前研究旨在测试鱼油补充的肌肉健康的挑战。

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