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Prediction of postoperative lung function in lung cancer patients using perfusion scintigraphy

机译:使用灌注闪烁术治疗肺癌患者术后肺功能的预测

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Background Predicting postoperative lung function is critical in lung cancer patients. Perfusion scintigraphy has been used to estimate postoperative function after lung resection. Purpose To evaluate the usefulness of the posterior oblique method in relation to other conventional processing methods for predicting postoperative lung function using lung perfusion scintigraphy. Material and Methods Fifty-five patients with non-small-cell lung cancer who underwent lobectomy were enrolled. Forced expiratory volume in 1 s (FEV1) values were obtained from preoperative and postoperative pulmonary function tests. After performing lung perfusion scintigraphy, predicted FEV1 values were calculated using the segment, conventional, posterior, and posterior oblique methods. Postoperative FEV1 values were compared with predicted FEV1 values. Results The mean value of the preoperative FEV1 was 2.29 L and that of the postoperative FEV1 was 1.89 L. The mean values of the predicted postoperative FEV1 values for the segment, conventional, posterior, and posterior oblique were 1.83 L, 1.94 L, 1.88 L, and 1.89 L, respectively. Between the observed and predicted FEV1 values, there was a strong correlation without significant difference except for conventional method. Bland-Altman analysis showed that segment and posterior methods underestimated the FEV1, whereas conventional and posterior oblique methods overestimated the FEV1. Conclusion Predictions with each processing method of lung perfusion scintigraphy showed nearly similar results to the actual postoperative lung function. The posterior oblique method of lung perfusion scintigraphy showed a very small difference to such an extent as to be equal to the observed FEV1, implying that this method may be applied for predicting postoperative lung function in lung cancer patients.
机译:预测术后肺功能的背景在肺癌患者至关重要。灌注闪烁图已被用来估计肺切除后的术后功能。目的是评估后倾斜方法关于其他常规处理方法的用性,用于使用肺灌注闪烁术治疗术后肺功能的方法。招生了物质和方法55例非小细胞肺癌患者的患者。从术前和术后肺功能测试中获得了1 s(FEV1)值的强制呼气量。在进行肺灌注闪烁扫描后,使用该段,常规,后倾斜方法计算预测的FEV1值。将术后FEV1值与预测的FEV1值进行比较。结果术前FEV1的平均值为2.29L,术后FEV1的平均值为1.89 L.预测术后FEV1的平均值,常规,后斜率为1.83L,1.94L,1.88L。分别为1.89升。在观察和预测的FEV1值之间,除了传统方法之外,存在强烈的相关性而没有显着差异。 Bland-Altman分析表明,段和后验方法低估了FEV1,而常规和后倾斜方法高估了FEV1。结论与肺灌注闪烁扫描的每种加工方法的预测显示出与实际术后肺功能的几乎相似。肺灌注闪烁扫描的后倾斜方法显示出与观察到的FEV1等于观察到的FEV1的程度非常小的差异,这意味着该方法可以应用于预测肺癌患者的术后肺功能。

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