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首页> 外文期刊>AIDS care. >Psychological well-being and adherence to antiretroviral therapy among adolescents living with HIV in Zambia
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Psychological well-being and adherence to antiretroviral therapy among adolescents living with HIV in Zambia

机译：在赞比亚艾滋病毒艾滋病毒患者中青少年抗逆转录病毒治疗的心理福祉及依从性

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Physical and psychosocial changes during adolescence could influence the psychological well-being and adherence to antiretroviral therapy (ART) of adolescents living with HIV. However, few studies have assessed these two important issues in Zambia. This study aimed at addressing this gap by examining adolescents' depressive symptoms and ART adherence. This was a mixed-methods study conducted from April to July 2014. We recruited 200 adolescents, ages 15 to 19, who were already aware of their HIV status. We measured depressive symptoms using the short form of the Center for Epidemiologic Studies Depression Scale, and self-reported three-day adherence to ART. We performed logistic regression analysis to identify factors associated with depressive symptoms and non-adherence to ART. For qualitative data, we examined challenges over ART adherence using thematic analysis. Out of 190 adolescents, 25.3% showed high scores of depressive symptoms. Factors associated with depressive symptoms were unsatisfactory relationships with family (Adjusted Odds Ratio [AOR] 3.01; 95% Confidence Interval [CI] 1.20-7.56); unsatisfactory relationships with health workers (AOR 2.68; 95% CI 1.04-6.93); and experience of stigma (AOR 2.99; 95% CI 1.07-8.41). Of all participants, 94.2% were taking ART, but 28.3% were non-adherent. Factors associated with non-adherence to ART were loss of a mother (AOR 3.00; 95% CI 1.05-8.58) and lack of basic knowledge about HIV (AOR 3.25; 95% CI 1.43-7.40). Qualitative data identified the following challenges to ART adherence: management of medication, physical reactions to medicine, and psychosocial distress. The evidence suggests that depressive symptoms and non-adherence to ART were priority issues in late adolescence in Zambia. Health workers should be aware of these issues, and the care and treatment services should be tailored to respond to age-specific needs.
机译：青春期期间的身体和心理社会变化可能影响与艾滋病毒艾滋病毒的青少年抗逆转录病毒治疗（艺术）的心理福祉和粘附。然而，很少有研究评估赞比亚这两个重要问题。这项研究旨在通过检查青少年的抑郁症状和艺术遵守来解决这种差距。这是从2014年4月到7月进行的混合方法研究。我们招募了200岁的青少年，年龄15至19岁，已经知道他们的艾滋病毒状况。我们使用流行病学研究中心的短形式测量抑郁症状，并自我报告的为期三天的粘附。我们对逻辑回归分析进行了识别与抑郁症状相关的因素，并不遵守艺术。对于定性数据，我们使用主题分析检查了对艺术遵守的挑战。在190个中的青少年中，25.3％表现出高分的抑郁症状。与抑郁症状相关的因素与家庭关系不满意（调整的赔率比[AOR] 3.01; 95％置信区间[CI] 1.20-7.56）;与卫生工作者的关系不满意（AOR 2.68; 95％CI 1.04-6.93）;和耻辱的经验（AOR 2.99; 95％CI 1.07-8.41）。在所有参与者中，94.2％正在采取艺术，但28.3％是非粘附的。与非遵守艺术相关的因素被丢失（AOR 3.00; 95％CI 1.05-8.58），缺乏关于艾滋病毒的基本知识（AOR 3.25; 95％CI 1.43-7.40）。定性数据确定了艺术遵守的以下挑战：药物管理，医学和心理社会痛苦的身体反应。证据表明，抑郁症状和非遵守艺术是赞比亚晚期青春期的优先问题。卫生工作者应该了解这些问题，应当根据特定年龄需求进行调整保健和治疗服务。

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