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History of Maternal Recognition of Pregnancy

机译:孕产妇识别怀孕

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The mechanism for signaling pregnancy recognition is highly variable among species, and the signaling molecule itself varies between estrogens in pigs to chorionic gonadotrophin in primates. This chapter provides insight into the menstrual cycle of women and estrous cycles of rodents, dog, cat, pigs, sheep, rabbits, and marsupials, as well as the hormones required for pregnancy recognition. Pregnancy recognition involves specific hormones such as prolactin in rodents or interferons in ruminants and estrogens in pigs that in their own way ensure the maintenance of the corpus luteum and its secretion of progesterone which is the hormone of pregnancy. However, these pregnancy recognition signals may also modify gene expression in a cell-specific and temporal manner to ensure the growth and development of the conceptus. This chapter provides some historical aspects of the development of understanding of mechanisms for the establishment and maintenance of pregnancy in several species of mammals.
机译:信号传导妊娠识别的机制在物种之间具有高度可变的变化,并且信号分子本身在猪中的雌激素与绒毛膜促性腺中的雌激素之间变化。本章介绍了对妇女的月经周期和啮齿动物,狗,猫,猪,羊,兔子和饲养的破坏性周期以及怀孕识别所需的激素。妊娠识别涉及特定的激素,例如啮齿动物或反刍动物干扰素和猪中的干扰素,其自行方式确保维持妊娠中的孕激素和孕酮的分泌物。然而,这些妊娠识别信号还可以以细胞特异性和时间方式修饰基因表达,以确保概念的生长和发展。本章提供了在几种哺乳动物中建立和维持怀孕机制的理解的一些历史方面。

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