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首页> 外文期刊>Aging clinical and experimental research >Usefulness of systolic blood pressure combined with heart rate measured on admission to identify 1-year all-cause mortality risk in elderly patients firstly hospitalized due to acute heart failure
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Usefulness of systolic blood pressure combined with heart rate measured on admission to identify 1-year all-cause mortality risk in elderly patients firstly hospitalized due to acute heart failure

机译：收缩性血压的有用性与在入院时测量的心率，以确定老年患者的1年全因死亡率风险，首先因急性心力衰竭住院治疗

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Background Systolic blood pressure (SBP) and heart rate (HR) are well-known prognostic factors in heart failure (HF). Aims Our objective was to assess the value of the combination of admission SBP and HR to estimate 1-year mortality risks in elderly patients admitted due to a first episode of acute HF (AHF). Methods During a 36-month period, we retrospectively reviewed 901 consecutive patients aged >= 75 admitted because of a first episode of AHF. According to admission SBP-HR combinations, three groups were defined: "low-risk" (HR = 140 mmHg), "moderate-risk" (HR = 70 bmp and SBP >= 120 mmHg), and "high-risk" (HR >= 70 bpm and SBP < 120 mmHg). We analyzed all-cause mortality using Cox mortality analysis. Results One-year mortality ranged from 16.5% for patients in the low-risk group to 50% for those in the high-risk group (p < 0.0001). Multivariate Cox regression for 1-year mortality showed hazard risk (HzR) ratios, compared to that (HzR 1) of the low-risk reference group, of 1.759 (95% CI 1.035-2.988, p = 0.037) for moderate-risk, and 3.171 (95% CI 1.799-5.589, p = 0.0001) for high-risk group. Prior use of a high number of chronic therapies (HzR 1.045), lower admission diastolic BP (HzR 0.986) and higher admission serum potassium values (HzR 1.534) were also significantly associated with mortality. Conclusion In elderly population firstly hospitalized due to AHF, the simple combined admission measurement of SBP and HR predicts higher risk for 1-year all-cause mortality.
机译：背景技术收缩压（SBP）和心率（HR）是心力衰竭（HF）的众所周知的预后因子。旨在我们的目标是评估入院SBP和人力资源组合的价值，以估计由于急性HF（AHF）的第一集而入院的老年患者的1年死亡率风险。方法在36个月期间，我们回顾性地审查了901名令人患者的901名≥75岁，因AHF的第一集被录取。根据入院SBP-HR组合，定义了三组：“低风险”（HR = 140mmHg），“中等风险”（HR = 70bmp和SBP> = 120 mmH），以及“高风险”（ HR> = 70bpm和SBP <120 mmHg）。我们使用COX死亡率分析了全因死亡率。结果低风险组中的患者为期一年的死亡率从16.5％到高风险群体中的50％（P <0.0001）。对于1年死亡率的多变量Cox回归显示出危险风险（HZR）比率，而低风险参考组的（HZR 1）为1.759（95％CI 1.035-2.988，P = 0.037），适用于中等风险，高风险组和3.171（95％CI 1.799-5.589，P = 0.0001）。在使用大量慢性疗法（HZR 1.045）之前，较低的入院舒张BP（HZR 0.986）和更高的入院血清钾值（HZR 1.534）也与死亡率显着相关。结论在老年人口首次因AHF而入院，SBP和人力资源的简单综合入场测量预测1年全导致死亡率的风险较高。

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