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Biotransformation of organic acids to their corresponding alcohols by Thermoanaerobacter pseudoethanolicus

机译:通过热腺杆菌伪乙醇对其相应醇的生物转化

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摘要

Higher order alcohols, such as 1-butanol and 1-hexanol, have a large number of applications but are currently prepared from non-renewable feedstocks. Here, the ability of Thermoanaerobacter pseudoethanolicus to reduce short-chain fatty acids to their corresponding alcohols using reducing potential generated by glucose catabolism with yields between 21.0 and 61.0%. C-13-labelled acetate, 1-propionate and 1-butyrate demonstrates that exogenously added fatty acids are indeed reduced to their corresponding alcohols. This mode of producing primary alcohols from fatty acids using a thermophilic anaerobe opens the door for the production of such alcohols from low-value materials using an inexpensive source of reducing potential. (C) 2019 Elsevier Ltd. All rights reserved.
机译:高阶醇,如1-丁醇和1-己醇,具有大量应用,但目前由不可再生原料制备。 在此,使用葡萄糖分解代谢产生的降低潜力在21.0和61.0%之间的降低潜力,热腺杆菌伪乙醇对其相应的醇减少短链脂肪酸的能力。 C-13标记的乙酸盐,1-丙酸盐和1-丁酸盐表明外源添加的脂肪酸确实还原为它们的相应醇。 使用嗜热厌氧产生从脂肪酸生产伯醇的模式打开门用于使用廉价的还原源从低价材料生产这些醇。 (c)2019年elestvier有限公司保留所有权利。

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