Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis

Chhabra Preeti; Spano Anthony J.; Bowers Daniel; Ren Tiantian; Moore Daniel J.; Timko Michael P.; Wu Martin; Brayman Kenneth L.

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Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis

机译：盲肠微生物组在免疫调节和稳态中的作用的证据

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Objective (s): Our objective was to investigate alterations in the cecal microbial composition during the development of type 1 diabetes (T1D) with or without IgM therapy, and correlate these alterations with the corresponding immune profile.

机译：目的：我们的目的是在有或没有IgM治疗的1型糖尿病（T1D）的发育过程中探讨肠道微生物组合物的改变，并将这些改变与相应的免疫分布相关。

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来源
《Annals of Surgery》 |2018年第3期|共9页
作者
Chhabra Preeti; Spano Anthony J.; Bowers Daniel; Ren Tiantian; Moore Daniel J.; Timko Michael P.; Wu Martin; Brayman Kenneth L.;
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作者单位

Univ Virginia Dept Surg Charlottesville VA USA;

Univ Virginia Dept Biol Charlottesville VA USA;

Univ Virginia Dept Surg Charlottesville VA USA;

Univ Virginia Dept Biol Charlottesville VA USA;

Vanderbilt Univ Dept Pediat Charlottesville VA USA;

Univ Virginia Dept Biol Charlottesville VA USA;

Univ Virginia Dept Biol Charlottesville VA USA;

Univ Virginia Dept Surg Charlottesville VA USA;

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原文格式 PDF
正文语种 eng
中图分类外科学;
关键词
type 1 diabetes mellitus; cecal microbiome; immune regulation;

机译：1型糖尿病;盲肠微生物组;免疫调节;

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专利

1. Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis [J] . Chhabra Preeti, Spano Anthony J., Bowers Daniel, Annals of Surgery . 2018,第3期

机译：盲肠微生物组在免疫调节和稳态中的作用的证据
2. Exercise and gut immune function: evidence of alterations in colon immune cell homeostasis and microbiome characteristics with exercise training [J] . Cook Marc D., Allen Jacob M., Pence Brandt D., Immunology and Cell Biology . 2016,第2期

机译：运动和肠道免疫功能：运动训练证明结肠免疫细胞稳态和微生物组特征改变的证据
3. Do immune complexes formed with autoantibodies have a role in the maintenance of immune homeostasis through interaction with FC receptors. [J] . Guarnotta G, Burgio VL, Triolo G Autoimmunity . 2000,第3期

机译：与自身抗体形成的免疫复合物是否通过与FC受体的相互作用在维持免疫稳态中起作用？
4. Interplay of Nutrients and Microbial Metabolites in Intestinal Immune Homeostasis: Distinct and Common Mechanisms of Immune Regulation in the Small Bowel and Colon [C] . Jacqueline Perrigoue, Anuk Das, J. Rodrigo Mora Nestlé Nutrition Workshop . 2014

机译：肠免疫稳态中营养和微生物代谢物的相互作用：小肠和结肠中免疫调节的明显和常见机制
5. Il-2-Dependent Regulation of Immune Homeostasis and Response to Infection [D] . Hayes, Erika Therese. 2021

机译：IL-2依赖性调节免疫稳态和对感染的反应
6. Role of Gut Microbiota Gut-Brain and Gut Liver Axes in Physiological Regulation of Inflammation Energy Balance and Metabolism: Diabetes-associated alterations in the cecal microbiome and metabolome are independent of diet or environment in the UC Davis Type 2 Diabetes Mellitus Rat model [O] . Brian D. Piccolo, James L. Graham, Kimber L. Stanhope, -1

机译：肠道菌群肠道脑和肠道肝轴在炎症能量平衡和代谢的生理调节中的作用：在UC戴维斯2型糖尿病大鼠模型中盲肠微生物组和代谢组的糖尿病相关变化与饮食或环境无关
7. Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis. [O] . Toms, C, Jessup, H, Thompson, C, 2008

机译：维持肠道免疫稳态和调节T细胞依赖性结肠炎不需要Gpr83表达。

Evidence for the Role of the Cecal Microbiome in Maintenance of Immune Regulation and Homeostasis

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