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首页> 外文期刊>Arthritis research & therapy. >Non-steroidal anti-inflammatory drugs and their benefits and harms: the challenge of interpreting meta-analyses and observational data sets when balanced data are not analyzed and reported
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Non-steroidal anti-inflammatory drugs and their benefits and harms: the challenge of interpreting meta-analyses and observational data sets when balanced data are not analyzed and reported

机译:非甾体类抗炎药及其益处和危害:在未分析和报告平衡数据时解释元分析和观测数据集的挑战

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摘要

A multitude of reports have delineated the risks of using non-steroidal anti-inflammatory drugs but have not been totally congruent. Meta-analyses of randomized controlled trials sometimes concur regarding gastrointestinal risk and cardiovascular risk but rarely report a balance of these risks for any one drug. Benefits measured in these studies are usually not reported. Observational data sets, supposedly reflective of ‘real world’ patients, do not always agree with the randomized controlled trial reports. Clinicians need assessments measuring the balance of harms and benefits so that better decisions based on their patients’ unique risk factors can be reached.
机译:众多报告已经描绘了使用非甾体类抗炎药的风险,但没有完全一致。 随机对照试验的荟萃分析有时有关于胃肠道风险和心血管风险的同意,但很少报告任何一种药物的风险的平衡。 通常没有报告在这些研究中测量的益处。 观察数据集,据说反映了“现实世界”患者,并不总是同意随机对照试验报告。 临床医生需要评估衡量危害和福利的平衡,以便可以达到基于患者独特的风险因素的更好的决策。

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