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Assessment of EEG as a Diagnostic and Prognostic Indicator Tool in the Febrile Seizures

机译:EEG评估FERILE癫痫发作中的诊断和预后指标工具

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Objective: To assess the sensitivity, specificity, and predictive value of EEG as a diagnostic and prognostic tool in the febrile seizures. Method: This study was conducted on 50 consecutive children with febrile seizures attending the pediatric OPD of a tertiary care hospital. The children were prospectively identified and EEG was carried out on two occasions. First EEG was done within one week of febrile seizure episode and second EEG was done after 03 months of first EEG. EEG records were obtained with the standard international protocols for duration of 35 minutes which included 25 minutes of sleep record in all the children. Photic stimulation, hyperventilation and sleep deprivation were used as activation procedures. Descriptive analysis of EEG tracings was done in terms of background activity and presence of abnormal waveforms. Result: Paroxysmal EEG abnormalities were present in 54% of children. Most common epileptiform discharges were of generalized epileptic discharge followed by focal polyspikes. Sleep deprivation was the most effective activation procedure in evaluating febrile seizure with abnormal epileptiform discharge patterns. Validity measures of EEG in febrile seizure were found to have 90% sensitivity, 70% specificity, 72% positive predictive value and 88% negative predictive value within 95% confidence interval. Conclusion: EEG is a sensitive method for identifying and quantifying electrical activity in febrile seizures. EEG is useful as a diagnostic and prognostic tool in febrile seizures and can provide information regarding presence of abnormalities, degree of encephalopathy and electrographic features but like all diagnostic tool it is not fully infallible and requires further alternative diagnostic and clinical support.
机译:目的:评估EEG的敏感性,特异性和预测值作为发热癫痫发作的诊断和预后工具。方法:本研究于连续50名患儿进行,发热癫痫发作,参加了第三级护理医院的儿科OPD。儿童被预先确定,脑电图有两次进行。第一个脑电图是在发热癫痫发作的一周内完成,第一个脑电图的03个月后第二脑电图。 eeg记录是通过标准的国际协议获得的,持续35分钟,其中包括所有儿童25分钟的睡眠记录。使用光刺激,过度通气和睡眠剥夺作为活化程序。 EEG描记的描述性分析是在背景活动和异常波形的存在方面完成的。结果:54%的儿童存在阵发性脑电图异常。最常见的癫痫株排出是普遍化癫痫发射,然后是焦点波动。睡眠剥夺是通过异常癫痫均放电模式评估发热癫痫发作的最有效的活化程序。发现脑梗死中的脑电图有效期措施具有90%的灵敏度,70%的特异性,72%的阳性预测值和95%置信区间内的88%的阴性预测值。结论:EEG是用于鉴定和定量发热癫痫发作中电活动的敏感方法。 EEG可用作发热癫痫发作的诊断和预后工具,并且可以提供关于异常的存在,脑病和张开学特性的信息,但与所有诊断工具一样,它不完全是可染色的并且需要进一步的替代诊断和临床支持。

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