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首页> 外文期刊>Inflammatory bowel diseases >Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis
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Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis

机译:持久性沙门氏菌肠道血鼠梗死感染诱导肠道纤维化期间的蛋白酶表达

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摘要

Background: Intestinal fibrosis is a common and serious complication of Crohn's disease characterized by the accumulation of fibroblasts, deposition of extracellular matrix, and formation of scar tissue. Although many factors including cytokines and proteases contribute to the development of intestinal fibrosis, the initiating mechanisms and the complex interplay between these factors remain unclear.
机译:背景:肠纤维化是克罗恩病的常见和严重并发症,其特征在于成纤维细胞积累,细胞外基质的沉积和瘢痕组织的形成。 虽然包括细胞因子和蛋白酶在内的许多因素有助于发育肠纤维化,但这些因素之间的起始机制和复杂的相互作用仍然尚不清楚。

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