Comparison between the efficacy of intralesional rituximab versus intralesional triamcinolone in the treatment refractory Pemphigus Vulgaris lesions: A randomized clinical trial

Iraji Fariba; Danesh Farzaneh; Faghihi Gita; Siadat Amirhossein; Mokhtari Fatemeh; Talakoob Mahboobeh; Hafezi Hossein

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Comparison between the efficacy of intralesional rituximab versus intralesional triamcinolone in the treatment refractory Pemphigus Vulgaris lesions: A randomized clinical trial

机译：腔内蓖麻毒素与腔内枝氨酮在治疗难治性Pemphigus的疗效之间的比较：随机临床试验

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Background: Pemphigus Vulgaris (PV) is a vesiculobullous autoimmune disorder characterized by production of autoantibody against cellular adhesion molecules. The treatment of PV is based on the use of systemic corticosteroid along with immunosuppressive therapy, but sometimes there are limited resistant lesions not responding to conventional systemic therapy. This double-blind, randomized clinical trial was designed to evaluate the efficacy of intralesional rituximab versus triamcinolone in treatment of the refractory scalp and mucosal pemphigus lesions.

机译：背景：Pemphigus Vulgaris（PV）是一种植物的自身免疫疾病，其特征是通过对细胞粘附分子产生自身抗体的影响。 PV的治疗是基于使用全身皮质类固醇以及免疫抑制治疗的使用，但有时耐受有限的病变没有响应常规的全身疗法。这种双盲随机临床试验旨在评估腔内Rituximab与Triamcinolone治疗难治性头皮和粘膜Pemphigus病变的疗效。

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来源
《International immunopharmacology》 |2019年第2019期|共4页
作者
Iraji Fariba; Danesh Farzaneh; Faghihi Gita; Siadat Amirhossein; Mokhtari Fatemeh; Talakoob Mahboobeh; Hafezi Hossein;
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作者单位

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

Isfahan Univ Med Sci Sch Med Dept Dermatol Esfahan Iran;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Pemphigus Vulgaris; Rituximab; Triamcinolone;

机译：Pemphigus Vulgaris;Rituximab;Triamcinolone;

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1. Comparison between the efficacy of intralesional rituximab versus intralesional triamcinolone in the treatment refractory Pemphigus Vulgaris lesions: A randomized clinical trial [J] . Iraji Fariba, Danesh Farzaneh, Faghihi Gita, International immunopharmacology . 2019,第期

机译：腔内蓖麻毒素与腔内枝氨酮在治疗难治性Pemphigus的疗效之间的比较：随机临床试验
2. Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial [J] . Khalid Farrukh Aslam, Mehrose Muhammad Younas, Saleem Muhammad, Burns: Including Thermal Injury . 2019,第1期

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3. Comparison of the efficacy of intralesional bleomycin versus intralesional triamcinolone acetonide in the treatment of keloids [J] . Khan Hina A, Sahibzada Mahmood N, Paracha Mohammad M Dermatologic therapy . 2019,第5期

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4. Curosurf versus survanta in the treatment of neonatal respiratory distress syndrome in preterm infants: results from a randomized, multicenter masked comparison trial. [C] . Acta pharmacologica sinica . 2002

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5. Comparison of the cost -effectiveness of triamcinolone acetonide (Azmacort HFA) and fluticasone propionate (Flovent) in adult asthmatics in a randomized controlled equivalence trial [D] . Lee, Todd Allen 2001

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机译：随机临床试验评价病灶内葡聚糖加硫酸镍与碘化葡糖胺加冷冻疗法治疗急性皮肤利什曼病的疗效
7. Intralesional Rituximab in the Treatment of Refractory Oral Pemphigus Vulgaris [O] . Keshavamurthy Vinay, Amrinder J. Kanwar, Ankit Mittal, 2015

机译：intralesional rituximab治疗难治性口服Pemphigus寻常症

Comparison between the efficacy of intralesional rituximab versus intralesional triamcinolone in the treatment refractory Pemphigus Vulgaris lesions: A randomized clinical trial

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