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首页> 外文期刊>International Journal of Microbiology >Antimicrobial Resistance of Salmonella enterica Serovars Typhi and Paratyphi Isolates from a General Hospital in Karawaci, Tangerang, Indonesia: A Five-Year Review
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Antimicrobial Resistance of Salmonella enterica Serovars Typhi and Paratyphi Isolates from a General Hospital in Karawaci, Tangerang, Indonesia: A Five-Year Review

机译：沙门氏菌的抗菌抗菌抗药菌和帕拉伐氏菌的抗菌抗药菌和帕拉伐氏菌在印度尼西亚坦曼塘塘塘（Karawaci）的综合医院：五年审查

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摘要

Typhoid and paratyphoid fever known as enteric fever pose important global public health problem, with 21.6 million cases and approximately 250,000 deaths annually. It is a prevalent disease in Indonesia, but data on the antimicrobial resistance pattern is limited. This study aim was to provide data on the antimicrobial resistance pattern of S. Typhi and S. Paratyphi bloodstream isolates in a general hospital in Karawaci, Tangerang, Banten, Indonesia, during the period of January 2011 to December 2015. Susceptibility against antimicrobials was detected according to the guidelines of the Clinical and Laboratory Standards Institute (CLSI). Out of a total of 168 isolates 55.4% were S. Typhi and 44.6% S. Paratyphi A. Most of the isolates, 92.9%, were from children aged 6–18 years and adult population. There was low resistance of S. Typhi against ampicillin, trimethoprim-sulfamethoxazole, ceftriaxone, ciprofloxacin, and levofloxacin, similar to previous studies in Indonesia. In the 2011–2015 period, resistance rates against most antimicrobials and MDR rate of S. Typhi and S. Paratyphi were low, emphasizing that there is a distinct epidemiological dynamic of the enteric fever in Indonesia.
机译：伤寒和副伤寒称为肠溶发热姿势重要的全球公共卫生问题，每年有2160万个病例和约250,000人死亡。它是印度尼西亚的普遍存在的疾病，但有关抗微生物抗性模式的数据是有限的。本研究目的是在2011年1月至2015年1月期间，提供有关卡拉瓦奇，坦纳港，唐登，巴纳登的综合医院抗菌抗菌模式的数据。根据临床和实验室标准研究所（CLSI）的指导方针。总共168分离株55.4％是S. Typhi和44.6％的帕拉伐氏A.大部分分离株92.9％来自6-18岁和成年人口。 S. Typhi对氨苄青霉素，三甲基巯基 - 磺胺甲氧唑，头孢哌酮，环丙沙星和左氧氟沙星的耐受性低，类似于前一种在印度尼西亚的研究。在2011 - 2015年期间，针对大多数抗微生物和MDR率的抗性率和S.帕拉氏菌的抗性率低，强调印度尼西亚肠溶存在鲜明的流行病学动态。

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