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首页> 外文期刊>International journal of psychophysiology: official journal of the International Organization of Psychophysiology >Resting-state alpha and gamma activity in affective disorder with ADHD symptoms: Comparison between bipolar disorder and major depressive disorder
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Resting-state alpha and gamma activity in affective disorder with ADHD symptoms: Comparison between bipolar disorder and major depressive disorder

机译：具有ADHD症状的情感障碍的休息状态α和γ活性：双相障碍与主要抑郁症之间的比较

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Although comorbid attention deficit/hyperactivity disorder (ADHD) symptoms are very common in mood disorder, its neurophysiological correlates have not been explored. This study aimed to examine clinical and neurophysiological correlates of ADHD symptoms in major depressive disorder (MDD) and bipolar disorder (BP). A total of 67 subjects with mood disorder, current depressive episode (38 subjects with MDD and 29 subjects with BP depression) were included in the analysis. Resting quantitative electroencephalography (qEEG) recordings were collected under eyes closed condition. ADHD symptoms, depression, anxiety, and lifetime hypomania were evaluated using self-report questionnaires. In MDD, ADHD symptoms did not show significant associations with anxiety and depression. In BP, ADHD symptoms showed significant associations with depression, anxiety and lifetime hypomania. Significant correlations with Adult ADHD self-report scales (ASRS) inattention score and total score were detected in left and right frontal alpha powers in MDD while significant correlation with ASRS hyperactivity score and ASRS total score were detected in right frontal gamma power in BP. Linear regression analyses revealed that left and right frontal alpha powers, depression and lifetime hypomania showed significant association with ASRS inattention score and ASRS total score in MDD. In BP, linear regression analysis showed ASRS hyperactivity score was associated with lifetime hypomania and the right frontal gamma power. MDD and BP showed different correlation patterns between frontal qEEG measures and ADHD symptoms. This might be associated with distinct neurobiological underpinnings of co-occurring ADHD symptoms in MDD and BP.
机译：虽然共聚注意力缺陷/多动障碍（ADHD）症状在情绪障碍中非常常见，但其神经生理学相关性尚未探讨。本研究旨在审查主要抑郁症（MDD）和双相障碍（BP）中ADHD症状的临床和神经生理学相关性。在分析中，共有67名患有情绪障碍的受试者，目前的抑郁症（38名患有MDD和29名受试者的受试者）。在眼睛关闭状态下收集休息定量的脑电图（QEEG）录音。使用自我报告问卷评估ADHD症状，抑郁症，焦虑和终身性高尚症状。在MDD中，ADHD症状并没有表现出与焦虑和抑郁症的重要协会。在BP中，ADHD症状显示出与抑郁症，焦虑和终身丑陋的重要协会。在MDD中的左侧和右前端α功率中检测到与成年人ADHD自我报告尺度（ASR）的显着相关性，同时在BP中的右前伽马电力中检测到与ASR多动评分和ASR总分比显着相关性。线性回归分析显示，左右额外α功率，抑郁症和终身丑陋症状与MDD中的ASRS分数和ASR总分比显着。在BP中，线性回归分析显示ASRS多动评分与寿命悬停和右前伽马电力相关。 MDD和BP在额外QEEG测量和ADHD症状之间显示出不同的相关模式。这可能与MDD和BP中的共同发生的ADHD症状的不同的神经生物学基础有关。

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