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首页> 外文期刊>European journal of cancer care >Interdisciplinary care programme to improve self-management for cancer patients undergoing stem cell transplantation: a prospective non-randomised intervention study
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Interdisciplinary care programme to improve self-management for cancer patients undergoing stem cell transplantation: a prospective non-randomised intervention study

机译：跨学科护理计划改善癌症患者的自我管理干细胞移植患者：预期非随机干预研究

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摘要

The purpose of this single-centre prospective non-randomised study was to evaluate the effectiveness of an interdisciplinary care programme to enhance self-management in patients with haematopoietic stem cell transplantation (HSCT). Patients undergoing HSCT, aged >14years with informed consent were recruited (n=79). Patients in the intervention group (IG) received standard care plus the SCION-HSCT intervention to counteract three problems after HSCT: muscle weakness, oral mucositis and malnutrition. Control group patients received standard care. Primary endpoint was global health-related quality of life (HRQoL) at discharge (EORTC QLQ C30 v. 3.0). Baseline characteristics were balanced between both groups, except physical performance (ECOG) being significantly lower for patients of the IG. At discharge, no group differences could be seen regarding HRQoL. Non-confirmatory post hoc analyses showed for patients of the IG a shorter duration of hospitalisation (MD -10.90; 95% CI -18.05 to -3.75) and increased activity during hospitalisation (MD 2.44; 95% CI 1.27-3.61). In conclusion, clinical effectiveness of the intervention could not be proven with respect to the aspired improvement of HRQoL. However, the nurse-led interdisciplinary caring programme could be carried out in every day ward routine. Further research should focus on working mechanisms of complex interventions aiming to improve HRQoL of patients undergoing HSCT.
机译：该单中心前瞻性非随机研究的目的是评估跨学科护理计划的有效性，以提高血液生成干细胞移植患者的自我管理（HSCT）。招募了接受HSCT的患者，年龄> 14岁及以上的知情同意书（n = 79）。干预组（IG）中的患者接受标准护理加上SCION-HSCT干预，以抵消HSCT后的三个问题：肌肉无力，口腔粘膜炎和营养不良。对照组患者接受标准护理。主要终点是放电时全球健康相关的生活质量（HRQOL）（EORTC QLQ C30 v.3.0）。除了Ig患者的体现（ECOG）外，两组之间的基线特征是平衡的。在放电时，可以在HRQOL中看到没有组差异。非核制性后HOC分析显示IG患者的住院时间较短（MD -10.90; 95％CI -18.05至-3.75）和住院期间的活性增加（MD 2.44; 95％CI 1.27-3.61）。总之，对于HRQOL的渴望改善，无法证明干预的临床效果。但是，护士LED跨学科关怀程序可以在每天进行病例进行。进一步的研究应专注于旨在改善接受HSCT患者的HRQOL的复杂干预的工作机制。

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  • 来源
    《European journal of cancer care》 |2017年第4期|共13页
  • 作者

    Schmidt H.; Boese S.; Bauer A.; Landenberger M.; Lau A.; Stoll O.; Schmoll H. -J.; Mauz-Koerholz C.; Kuss O.; Jahn P.;

  • 作者单位

    Martin Luther Univ Halle Wittenberg Inst Hlth &

    Nursing Sci Fac Med Magdeburger Str 8 D-06097;

    Martin Luther Univ Halle Wittenberg Inst Hlth &

    Nursing Sci Fac Med Magdeburger Str 8 D-06097;

    Martin Luther Univ Halle Wittenberg Inst Hlth &

    Nursing Sci Fac Med Magdeburger Str 8 D-06097;

    Martin Luther Univ Halle Wittenberg Inst Commun Media &

    Sports Dept Sports Sci Sports Sci Halle;

    Martin Luther Univ Halle Wittenberg Inst Commun Media &

    Sports Dept Sports Sci Halle Germany;

    Martin Luther Univ Halle Wittenberg Univ Hosp Halle Dept Hematol &

    Onkol Internal Med 4 Halle;

    Martin Luther Univ Halle Wittenberg Univ Hosp Halle Dept Childrens Oncol Halle Saale Germany;

    Heinrich Heine Univ Ctr Hlth &

    Soc Fac Med Inst Biometry &

    Epidemiol Dusseldorf Germany;

    Martin Luther Univ Halle Wittenberg Inst Hlth &

    Nursing Sci Fac Med Nursing Res Univ Hosp Halle;

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  • 正文语种 eng
  • 中图分类 肿瘤学;
  • 关键词

    stem cell transplantation; health-related quality of life; self-management; physical activation; mucositis;

    机译：干细胞移植;与健康有关的生活质量;自我管理;物理活化;粘膜炎;

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