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首页> 外文期刊>European Journal of Cell Biology: Journal of Deutsche Gesellschaft fur Elektronenmikroskopie: Journal of Deutsche Gesellschaft fur Zellbiologie >Cell polarization: From epithelial cells to odontoblasts
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Cell polarization: From epithelial cells to odontoblasts

机译：细胞偏振：从上皮细胞到Odontoblasts

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摘要

Cell polarity identifies the asymmetry of a cell. Various types of cells, including odontoblasts and epithelial cells, polarize to fulfil their destined functions. Odontoblast polarization is a prerequisite and fundamental step for tooth development and tubular dentin formation. Current knowledge of odontoblast polarization, however, is very limited, which greatly impedes the development of novel approaches for regenerative endodontics. Compared to odontoblasts, epithelial cell polarization has been extensively studied over the last several decades. The knowledge obtained from epithelia polarization has been found applicable to other cell types, which is particularly useful considering the remarkable similarities of the morphological and compositional features between polarized odontoblasts and epithelia. In this review, we first discuss the characteristics, the key regulatory factors, and the process of epithelial polarity. Next, we compare the known facts of odontoblast polarization with epithelial cells. Lastly, we clarify knowledge gaps in odontoblast polarization and propose the directions for future research to fill the gaps, leading to the advancement of regenerative endodontics.
机译：电池极性识别细胞的不对称性。各种类型的细胞，包括牙卵细胞和上皮细胞，极化以满足其定期功能。 Odontoblast偏振是牙齿发育和管状牙本质形成的先决条件和基本步骤。然而，目前对Odontoblast极化的认识非常有限，这极大地阻碍了新型胸腺功能的新方法的发展。与Odontoblast相比，在过去几十年中，上皮细胞极化已被广泛研究。已发现从上皮末端产生的知识适用于其他细胞类型，其特别有用，考虑到极化的牙卵细胞和上皮细胞之间的形态和组成特征的显着相似性。在本综述中，我们首先讨论了上皮极性的特征，关键调节因素和过程。接下来，我们与上皮细胞比较了Odontoblast偏振的已知事实。最后，我们澄清了Odontoblast极化中的知识差距，并提出了未来研究的指示，以填补差距，导致再生牙髓菌的进步。

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