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首页> 外文期刊>European radiology >Remote brain microhaemorrhages may predict haematoma in glioma patients treated with radiation therapy
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Remote brain microhaemorrhages may predict haematoma in glioma patients treated with radiation therapy

机译：远程脑部微鼻鼠可能预测胶质瘤患者的血肿患者治疗治疗治疗

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ObjectivesTo evaluate the prevalence of cerebral remote microhaemorrhages (RMH) and remote haematomas (RH) using magnetic resonance susceptibility-weighted imaging (SWI) among patients treated for gliomas during follow-up.MethodsWe conducted a retrospective single centre longitudinal study on 58 consecutive patients treated for gliomas from January 2009 through December 2010. Our institutional review board approved this study. We evaluated the presence and number of RMH and RH found outside the brain tumour on follow-up MR imaging. We performed univariate and bivariate analyses to identify predictors for RMH and RH and Kaplan-Meier survival analysis techniques.ResultsTwenty-five (43%) and four patients (7%) developed at least one RMH or RH, respectively, during follow-up. The risk was significantly higher for patients who received radiation therapy (49% and 8% versus 0%) (p = 0.02). The risk of developing RH was significantly higher in patients with at least one RMH and a high burden of RMH. The mean age of those presenting with at least one RMH or RH was significantly lower.ConclusionsRMH were common in adult survivors of gliomas who received radiation therapy and may predict the onset of RH during follow-up, mainly in younger patients.Key Points center dot Brain RMH and RH are significantly more likely to occur after RT.center dot RMH occur in almost half of the patients treated with RT.center dot RMH and RH are significantly more frequent in younger patients.center dot RH occur only in patients with RMH.
机译：Objectivesto评估使用磁共振易感性 - 加权成像（SWI）对脑膜瘤治疗的患者进行脑远程微观鼠鼠（RMH）和远程血红蛋白（RH）的患病率。在后续疗效中对58例治疗的连续患者进行了回顾性单中心纵向研究对于2009年1月至2010年12月的Gliomas。我们的机构审查委员会批准了这项研究。我们评估了在脑肿瘤外的rMH和RH的存在和数量在后续MR成像上。我们进行了单变量和双变量分析，以鉴定RMH和RH和Kaplan-Meier生存率分析技术的预测因子。在随访期间，分别产生至少一种RMH或RH（43％）和4名患者（7％）。接受放射治疗的患者（49％和8％对0％）的患者风险显着更高（P = 0.02）。至少有一个RMH和RMH负担的患者患者显着较高。呈现至少一个RMH或RH的那些的平均年龄显着降低。结肠ConclusionsRMH在接受放射治疗的Gliomas的成人幸存者中常见，并且可以预测在随访期间的RH发作，主要是较年轻的患者.Key点中心点RT.Center Dot RMH在较年轻的患者治疗的患者的几乎一半患者中发生脑RMH和RH显着发生。在较年轻的患者中，在较年轻的患者中显着更频繁。

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