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首页> 外文期刊>Medical image analysis >Statistical coronary motion models for 2D+t/3D registration of X-ray coronary angiography and CTA
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Statistical coronary motion models for 2D+t/3D registration of X-ray coronary angiography and CTA

机译：X射线冠状动脉造影和CTA的2D + T / 3D注册的统计冠状动脉运动模型

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摘要

Accurate alignment of intra-operative X-ray coronary angiography (XA) and pre-operative cardiac CT angiography (CTA) may improve procedural success rates of minimally invasive coronary interventions for patients with chronic total occlusions. It was previously shown that incorporating patient specific coronary motion extracted from 4D CTA increases the robustness of the alignment. However, pre-operative CTA is often acquired with gating at end-diastole, in which case patient specific motion is not available. For such cases, we investigate the possibility of using population based coronary motion models to provide constraints for the 2D + t/3D registration. We propose a methodology for building statistical motion models of the coronary arteries from a training population of 4D CTA datasets. We compare the 2D + t/3D registration performance of the proposed statistical models with other motion estimates, including the patient specific motion extracted from 4D CTA, the mean motion of a population, the predicted motion based on the cardiac shape. The coronary motion models, constructed on a training set of 150 patients, had a generalization accuracy of 1. mm root mean square point-to-point distance. Their 2D + t/3D registration accuracy on one cardiac cycle of 12 monoplane XA sequences was similar to, if not better than, the 4D CTA based motion, irrespective of which respiratory model and which feature based 2D/3D distance metric was used. The resulting model based coronary motion estimate showed good applicability for registration of a subsequent cardiac cycle.
机译：可操作X射线冠状动脉造影（XA）和术前心脏CT血管造影（CTA）的精确对准可以改善慢性总闭塞患者的微创冠状动脉干预的程序成功率。之前表明，从4D CTA提取的患者特异性冠状动脉运动增加了对准的鲁棒性。然而，通常在结束 - 舒张术处进行预次CTA，在这种情况下，在这种情况下，患者特定运动不可用。对于这种情况，我们研究了使用基于人口的冠状动脉运动模型的可能性，为2D + T / 3D配准提供约束。我们提出了一种从4D CTA数据集的训练群体构建冠状动脉统计运动模型的方法。我们将所提出的统计模型的2D + T / 3D登记性能与其他运动估计进行比较，包括从4D CTA提取的患者特定运动，群体的平均运动，基于心形的预测运动。在150名患者的训练组上构建的冠状动动运动模型具有1. mm均方的概括精度为1. mm均方向点距离。它们的2D + T / 3D注册精度在12个单柱XA序列的一个心动周期上类似于基于4D CTA的运动，而不管哪种呼吸模型以及使用哪种特征的2D / 3D距离度量。由此产生的基于模型的冠状动脉运动估计显示出良好的适用性，用于登记随后的心动周期。

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  • 来源
    《Medical image analysis》 |2013年第6期|共12页
  • 作者

    BakaN.; MetzC.T.; SchultzC.; NeefjesL.; vanGeunsR.J.; LelieveldtB.P.F.; NiessenW.J.; VanWalsumT.; DeBruijneM.;

  • 作者单位

    Biomedical Imaging Group Rotterdam Departments of Radiology and Medical Informatics Erasmus MC;

    Biomedical Imaging Group Rotterdam Departments of Radiology and Medical Informatics Erasmus MC;

    Department of Cardiology Erasmus MC Rotterdam Netherlands;

    Department of Radiology Erasmus MC Rotterdam Netherlands;

    Department of Radiology Erasmus MC Rotterdam Netherlands;

    Division of Image Processing Department of Radiology Leiden University Medical Center Leiden;

    Biomedical Imaging Group Rotterdam Departments of Radiology and Medical Informatics Erasmus MC;

    Biomedical Imaging Group Rotterdam Departments of Radiology and Medical Informatics Erasmus MC;

    Biomedical Imaging Group Rotterdam Departments of Radiology and Medical Informatics Erasmus MC;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 影像诊断学;
  • 关键词

    2D+t/3D+t registration; 2D/3D alignment; Reconstruction; Respiratory alignment; SSM;

    机译：2D + T / 3D + T登记;2D / 3D对齐;重建;呼吸对准;SSM;

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