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首页> 外文期刊>Monographs in clinical cytology. >Lymphohematopoietic and Histiocytic Tumors
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Lymphohematopoietic and Histiocytic Tumors

机译：淋巴化遗传和组织细胞瘤

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Plasma Cell Neoplasm: Solitary Plasmacytoma and Plasma Cell Myeloma: Plasma cell neoplasms of the bone constitute a spectrum of clonal proliferations of plasma cells, including plasma cell myeloma with osteolytic defects of the skeleton and monoclonal protein in the serum, and solitary plasmacytoma of bone, both composed of identical neoplastic plasma cells. The cytologic and immunocytochemical features of cells from solitary plasmacytoma of bone are indistinguishable from those of multiple myeloma of bone. Solitary plasmacytoma and plasma cell myeloma represent the most common primary bone neoplasms. Plasma cell myeloma arises predominantly in elderly patients with a peak of incidence in the sixth and seventh decades of life and is very rare in individuals younger than 40 years of age. Solitary plasmacytoma occurs in somewhat younger patients with a median age of 55 years and a male to female ratio of approximately 2:1. Those lesions are most common in bones with active hematopoiesis such as the vertebrae, ribs, skull, femur, pelvic bones, scapula, and clavicle.
机译：血浆细胞肿瘤：孤立性血浆和血浆细胞骨髓瘤：骨的血浆细胞肿瘤构成血浆细胞的克隆增殖的光谱，包括血浆细胞骨髓瘤，血清中骨骼和单克隆蛋白质的骨溶缺损，以及骨骼的孤立性等离子体胞质瘤，两个由相同的肿瘤血浆细胞组成。来自骨骼孤立性血浆的细胞的细胞学和免疫细胞化学特征与多种骨骼骨髓瘤的细胞难以区分。孤立性血浆和血浆细胞骨髓瘤代表最常见的原发性骨肿瘤。血浆细胞骨髓瘤主要是在第六和第七十年生命中发病率的高峰期，在40岁以下的人群中非常罕见。孤独的血浆胞质胞瘤发生在稍微患有55岁的中位数，男性与女性比例约为2：1的患者。这些病变在骨骼中最常见，具有活性血液，如椎骨，肋骨，头骨，股骨，盆腔，肩胛骨和锁骨。

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