AR variants: lost in translation to clinical practice?

Handle Florian; Claessens Frank

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AR variants: lost in translation to clinical practice?

机译：AR Variants：丢失在翻译到临床实践？

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The concept that resistance against androgen receptor (AR) signalling inhibitors is explained by AR variants (ARVs) has spread as a seductive meme. However, two problems have delayed the translation of these findings to clinical practice: the complexity of the mechanism of action and the challenging development of clinical decision- making tools involving ARVs.

机译：通过Ar变体（ARV）解释抗雄激素受体（AR）信号传导抑制剂的概念（ARV）作为诱人的MEME扩散。然而，两个问题延迟了这些调查结果的翻译给临床实践：行动机制的复杂性以及涉及ARV的临床决策工具的挑战性。

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来源
《Nature reviews. Urology》 |2019年第8期|共2页
作者
Handle Florian; Claessens Frank;
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作者单位

Katholieke Univ Leuven Mol Endocrinol Lab Dept Cellular &

Mol Med Leuven Belgium;

Katholieke Univ Leuven Mol Endocrinol Lab Dept Cellular &

Mol Med Leuven Belgium;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. AR variants: lost in translation to clinical practice? [J] . Handle Florian, Claessens Frank Nature reviews. Urology . 2019,第8期

机译：AR Variants：丢失在翻译到临床实践？
2. Primary Prevention of Heart Failure in Patients With Type 2 Diabetes Mellitus: Lost in Translation Between Clinical Trial Design, Regulatory Standards, and Practice Guidelines [J] . Greene Stephen J., Butler Javed Circulation: An Official Journal of the American Heart Association . 2019,第2期

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3. Lost in translation: Interpreting cardiac muscle mechanics data in clinical practice [J] . Mamidi Ranganath, Li Jiayang, Doh Chang Yoon, Archives of Biochemistry and Biophysics . 2019,第期

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4. Medical diagnosis lost in translation - Analysis of uncertainty and negation expressions in English and Swedish clinical texts [C] . Danielle L Mowery, Sumithra Velupillai, Wendy W Chapman 11th Workshop on biomedical natural language processing 2012 . 2012

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5. Lost in Translation: Monolingual and Bilingual Supervisors' Lived Experiences in Clinical Supervision with Student Counselors Counseling Spanish-Speaking Clients [D] . Rubio, Julieta. 2017

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7. Lost in translation: Interpreting cardiac muscle mechanics data in clinical practice [O] . Ranganath Mamidi, Jiayang Li, Chang Yoon Doh, 2019

机译：丢失翻译：解释临床实践中的心肌力学数据

AR variants: lost in translation to clinical practice?

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