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Hypercalcaemia during pregnancy: Review of maternal and fetal complications, investigations, and management

机译:怀孕期间高钙血症:审查孕产妇和胎儿并发症,调查和管理

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Introduction Asymptomatic mild primary hyperparathyroidism is increasingly being identified during pregnancy. Recent studies have demonstrated inconsistent findings with regard to pregnancy complications and the need for surgical intervention during pregnancy. Method A retrospective audit of outcomes of pregnancies complicated by hypercalcaemia over a 15-year period was performed. Results Twenty-nine pregnancies to 26 women with hypercalcaemia were identified, corresponding to 37 cases per 100,000 deliveries. Hypercalcaemia was due to primary hyperparathyroidism in 90% of cases, with mean serum calcium of 2.89 mmol/l and mean ionised calcium 1.43 mmol/l. Four women underwent successful neck exploration during pregnancy. Pregnancy complications were limited to three cases of pre-eclampsia and one case of symptomatic neonatal hypoparathyroidism. Conclusion Close observation without surgical intervention would seem reasonable in women with mild hypercalcaemia during pregnancy.
机译:引言在怀孕期间越来越多地确定无症状轻度原发性甲状旁腺功能亢进。 最近的研究表明,关于妊娠并发症的表现不一致,并在怀孕期间需要手术干预。 方法进行了在15年期间过度血肿复杂的怀孕结果的回顾性审核。 结果,鉴定了26例高钙血症26名妇女的怀孕,对应于每10万次交付的37例。 高钙血症是由于90%的案件中原发性甲状旁腺功能亢进,平均血清钙为2.89mmol / L,平均电离钙1.43mmol / L. 四名妇女在怀孕期间接受了成功的颈部探索。 妊娠并发症仅限于出版前的三种情况和症状新生儿过症状功能亢进的一个病例。 结论没有手术干预的密切观察似乎是怀孕期间患有轻微高钙血症的妇女。

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