Hyaluronan-mediated motility receptor (RHAMM) immunohistochemical expression and androgen deprivation in normal peritumoral, hyperplasic and neoplastic prostate tissue.

Fernando Korkes; Marilia Germanos de Castro; Stenio de Cassio Zequi; Lívia Nardi; Auro Del Giglio; Antonio Carlos de Lima Pompeo

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Hyaluronan-mediated motility receptor (RHAMM) immunohistochemical expression and androgen deprivation in normal peritumoral, hyperplasic and neoplastic prostate tissue.

机译：透明质酸介导的运动受体（RHAMM）免疫组织化学表达和雄激素剥夺在正常的肿瘤周围，增生和赘生性前列腺组织中。

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RHAMM expression in prostate cancer is directly associated with ADT. Significant RHAMM expression occurs as early as after 1 month of ADT and progressively increases with ADT duration. When prostate cancer becomes CRPC, RHAMM expression is higher. RHAMM expression was not associated with prostate cancer prognostic factors. RHAMM overexpression may contribute to the development of hormonal resistance in prostate cancer.

机译：RHAMM在前列腺癌中的表达与ADT直接相关。 RHAMM的显着表达最早在ADT 1个月后出现，并随着ADT持续时间的增加而逐渐增加。当前列腺癌变为CRPC时，RHAMM表达更高。 RHAMM表达与前列腺癌的预后因素无关。 RHAMM过表达可能有助于前列腺癌中荷尔蒙抵抗的发展。

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《BJU international》 |2014年第5期|共8页
作者
Fernando Korkes; Marilia Germanos de Castro; Stenio de Cassio Zequi; Lívia Nardi; Auro Del Giglio; Antonio Carlos de Lima Pompeo;
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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. Hyaluronan-mediated motility receptor (RHAMM) immunohistochemical expression and androgen deprivation in normal peritumoral, hyperplasic and neoplastic prostate tissue. [J] . Fernando Korkes, Marilia Germanos de Castro, Stenio de Cassio Zequi, BJU international . 2014,第5期

机译：透明质酸介导的运动受体（RHAMM）免疫组织化学表达和雄激素剥夺在正常的肿瘤周围，增生和赘生性前列腺组织中。
2. The receptor for hyaluronan-mediated motility (RHAMM) expression in neonatal bronchiolar epithelium correlates negatively with lung air content [J] . Laszlo Markasz, Rashmin C. Savani, Gunnar Sedin, Early human development . 2018,第期

机译：透明质酸癌的受体介导的新生儿支气管上皮中的运动（RHAMM）表达与肺空气含量负相关
3. Expression of the hyaluronan-mediated motility receptor RHAMM in tumor budding cells identifies aggressive colorectal cancers [J] . Koelzer Viktor Hendrik, Huber Bettina, Mete Valentina, Human Pathology . 2015,第11期

机译：透明质酸介导的运动受体RHAMM在肿瘤出芽细胞中的表达确定了侵袭性大肠癌
4. Expression of Estrogen a and p Variants, Androgen, and Progesterone Receptors in Human Normal and Neoplastic Endometrium [C] . Maciej Skrzypczak, Sylwia Zagulska-Szymczak, Rosette Lidereau, International Symposium on Hormonal Carcinogenesis . 2005

机译：雌激素A和P变种，雄激素和孕酮受体在人正常和肿瘤子宫内膜中的表达
5. MED19 Alters Genomic Occupancy of the Androgen Receptor and Gene Expression in Prostate Cancer Cells, Driving Growth under Low Androgen [D] . Weber, Hannah. 2020

机译：Med19改变了前列腺癌细胞中雄激素受体和基因表达的基因组占据，在低雄激素下促进生长
6. Immunohistochemical analysis of RHAMM expression in normal and neoplastic human tissues: a cell cycle protein with distinctive expression in mitotic cells and testicular germ cells [O] . Yao-Tseng Chen, Zhengming Chen, Yi-Chieh Nancy Du 2018

机译：正常和赘生性人类组织中RHAMM表达的免疫组织化学分析：在有丝分裂细胞和睾丸生殖细胞中有独特表达的细胞周期蛋白
7. Hyaluronan-dependent motility of B cells and leukemic plasma cells in blood, but not of bone marrow plasma cells, in multiple myeloma: alternate use of receptor for hyaluronan-mediated motility (RHAMM) and CD44 [O] . A Masellis-Smith, AR Belch, MJ Mant, 1996

机译：B细胞和白血病血浆细胞的透明质运动依赖于血液中的血糖等离子体细胞，在多种骨髓瘤中：交替使用受体用于透明质酸介导的运动（RHAMM）和CD44

Hyaluronan-mediated motility receptor (RHAMM) immunohistochemical expression and androgen deprivation in normal peritumoral, hyperplasic and neoplastic prostate tissue.

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