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Endocrinological Roles for Testosterone in Resistance Exercise Responses and Adaptations

机译：耐药酮的内分泌作用，抵抗运动反应和适应

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摘要

Chronic increases in testosterone levels can significantly increase hypertrophy and strength, as has been demonstrated by pharmacological intervention. However, decreases in basal testosterone levels can have the opposite result, as has been seen in hypogonadal populations. Because of these profound effects on hypertrophy and strength, testosterone has often been studied in conjunction with resistance exercise to examine whether the endocrine system plays a role in adaptations to the stimulus. Whereas some studies have demonstrated a chronic increase in basal testosterone, others have failed to find an adaptation to regular resistance exercise. However, improvements in strength and hypertrophy appear to be possible regardless of the presence of this adaptation. Testosterone has also been shown to acutely rise immediately following an acute resistance exercise bout. While this substantial mobilization of testosterone is brief, its effects are seen for several hours through the upregulation of the androgen receptor. The role of this acute response at present is unknown, but further study of the non-genomic action and possible intracrinological processes is warranted. This response does not seem to be necessary for resistance training adaptations to occur either, but whether this response optimizes such adaptations has not yet been determined.
机译：正如药理干预所证明的那样，睾酮水平的慢性增加可以显着增加肥大和强度。然而，基础睾酮水平的降低可以具有相反的结果，如低因子群体所示。由于这些对肥大和强度的深刻影响，睾酮通常与抗性运动结合研究，以检查内分泌系统是否在适应刺激方面发挥作用。虽然一些研究表明了基础睾酮的慢性增加，但其他研究未能找到对常规阻力运动的适应。然而，无论这种适应的存在，强度和肥大的改善似乎是可能的。在急性抵抗运动中，睾酮也已被证明急性升高。虽然这种大量动员睾酮是简短的，但通过雄激素受体的上调，它的效果几小时被观察了几个小时。目前这种急性反应的作用是未知的，但有权进一步研究非基因组作用和可能的术治过程。这种响应似乎不需要发生电阻训练适应，但是这种响应是否优化了这种适应尚未确定。

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  • 来源
    《Sports medicine》 |2017年第9期|共12页
  • 作者

    Hooper David R.; Kraemer William J.; Focht Brian C.; Volek Jeff S.; DuPont William H.; Caldwell Lydia K.; Maresh Carl M.;

  • 作者单位

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

    Ohio State Univ Dept Human Sci A054 PAES Bldg 305 Annie &

    John Glenn Ave Columbus OH 43210 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 运动医学;
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