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Preface: The Changing Landscape of Pancreatic Pathology

机译:序言:胰腺病理的变化景观

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The practice of pancreatic pathology has evolved significantly in recent years. In this issue, we provide an update into the major diagnostic entities in the pancreas, including both neoplastic and nonneoplastic diseases. In addition, we provide correlations with other specialties of relevance to the practicing pathologist. We first focus on gross dissection of pancreatic resection specimens, as this process lays the groundwork for accurate diagnosis. We then discuss the process that resulted in the gross specimen by highlighting advances in surgery that are relevant to the practicing pathologist. Then, we turn to the tumors of the pancreas, which represent the entities encountered most commonly in practice-these include pancreatic adenocarcinoma (and variants), precursor lesions, nonductal cancers, and neuroendocrine tumors. Next, we cover benign pancreatic lesions, including pancreatitis and benign masses. We then focus on other pathologic analyses that are commonly used on the pancreas, including cytopathology and cyst fluid analysis. Finally, we highlight the molecular genetics of pancreatic neoplasms, a field that has advanced greatly in recent years, and discuss genetic syndromes with pancreatic manifestations. This broad update is intended for practicing pathologists in order to capture the critical advances in recent years.
机译:近年来胰腺病理学的实践显着发展。在此问题中,我们提供了胰腺中主要诊断实体的更新,包括肿瘤和非宝挥疾病。此外,我们与与实践病理学家相关的其他特派提供相关性。我们首先专注于胰切除标本的总解剖,因为该过程为准确诊断奠定了基础。然后,我们讨论通过突出与练习病理学家相关的手术的进展来讨论导致毛标本的过程。然后,我们转向胰腺的肿瘤,这代表了在实践中最常遇到的实体 - 这些包括胰腺腺癌(和变体),前体病变,导电癌和神经内分泌肿瘤。接下来,我们涵盖良性胰腺病变,包括胰腺炎和良性群众。然后,我们专注于胰腺常用的其他病理分析,包括细胞病变和囊肿流体分析。最后,我们突出了胰腺炎的分子遗传学,近年来大大提高的领域,并讨论了胰腺表现的遗传综合征。这一广泛的更新旨在练习病理学家,以旨在捕捉近年来的关键进步。

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