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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Prophylactic pulmonary vein isolation during cavotricuspid isthmus ablation for atrial flutter: A meta‐analysis
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Prophylactic pulmonary vein isolation during cavotricuspid isthmus ablation for atrial flutter: A meta‐analysis

机译：预防性肺静脉分离在神经颤动中的Cavotricspid氨疹烧蚀过程中：荟萃分析

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Abstract Background Atrial arrhythmias (AA), including atrial fibrillation (AF), have been reported in patients after cavotricuspid isthmus (CTI) ablation for typical atrial flutter (AFL). Several studies have examined the effect of performing concomitant pulmonary vein isolation (PVI) with CTI on recurrent AA. These studies were analyzed to determine the overall effect of this approach on recurrent AA. Methods PubMed and Google Scholar were searched for randomized trials comparing the incidence of AA after CTI versus CTI + PVI until June 2018. Only patients without prior history of AF were included in the recurrent AA analysis. All patients were included in the analyses of other clinical outcomes. Results Four randomized control trials were included in the meta‐analysis. In the recurrent AA analysis, a total of 314 patients were randomized in the studies ( n ?=?158 CTI, n ?=?156 CTI + PVI). Freedom from AA at 1 year was significantly higher in the CTI + PVI group versus CTI alone (odds ratio [OR] 0.25 [0.14, 0.44] 95% confidence interval [CI], P ??0.00001). A total of 550 patients ( n ?=?336 CTI, n ?=?214 CTI + PVI) were included in analyses for procedure time, fluoroscopy time, and complications rates. Procedure time and fluoroscopy time were significantly longer in the CTI + PVI group (mean difference [MD]: 103.31 min [94.40, 112.23] 95% CI, P ??0.00001) and (MD: 16.47 min [14.89, 18.05] 95% CI, P ??0.00001), respectively. Total complications were statistically similar between groups. Conclusion This meta‐analysis shows addition of a prophylactic PVI during CTI ablation significantly reduces recurrent AA at 1 year without significantly increasing major complications.
机译：摘要背景典型心房扑除（AFL）后患者报道了在患者的患者中报道了心房心律失常（AA），包括心房颤动（AF）。几项研究检测了在复发AA上用CTI进行伴随肺静脉分离（PVI）的效果。分析这些研究以确定这种方法对复发性AA的总体效果。方法采用CTI与CTI + PVI后AA发生率的随机试验搜索PubMed和Google Scholar，直到2018年6月。尚未患有AF的现有历史的患者。所有患者均包含在其他临床结果的分析中。结果荟萃分析中包括四项随机对照试验。在复发性AA分析中，共有314名患者在研究中随机化（N？=？158 CTI，N？= 156 CTI + PVI）。 CTI + PVI组对1年的AA自由度与CTI相比显着高（OPES比率[或] 0.25 [0.14,0.44] 95％置信区间[CI]，P≥≤0.00001）。共有550名患者（n？=Δ336cti，n？= 214 cti + pvi）含有术语时间，透明度时间和并发症率的分析。 CTI + PVI组（平均差异[MD]：103.31分钟[94.40,112.23] 95％CI，P = 0. <0.00001）和（MD：16.47分钟[14.89,18.05] 95％CI，P？<0.00001）。组之间的总并发症在统计学上相似。结论该荟萃分析显示CTI消融期间的预防性PVI在1年内显着减少了复发性AA，而不会显着增加主要并发症。

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