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首页> 外文期刊>Paediatrics and international child health >Gastro-intestinal basidiobolomycosis in a 2-year-old boy: dramatic response to potassium iodide
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Gastro-intestinal basidiobolomycosis in a 2-year-old boy: dramatic response to potassium iodide

机译：胃肠碱性碱菌霉菌在一个2岁的男孩中：对碘化钾的戏剧反应

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摘要

Gastro-intestinal basidiobolomycosis (GIB) is a rare fungal infection caused by Basidiobolus ranarum. Treatment includes surgical resection and long-term antifungal therapy. A 2.5-year-old boy presented with a 10-day history of abdominal pain, fever and diarrhoea, and a palpable abdominal mass was detected. Resection was undertaken and histology confirmed basidiobolomycosis. Treatment with amphotericin B and itraconazole was commenced, but the infection progressed and spread to involve the intestines, liver, ribs and lung, and also the abdominal wall after-6 months, requiring fou r operative procedures. Because of unresponsiveness to amphotericin and itraconazole, oral potassium iodide was added which resulted in complete resolution of the infection. Potassium iodide is an essential component of the treatment of systemic B. ranarum.
机译：胃肠嗜酸盐碱菌（GIB）是由巴萨鲁姆碱引起的罕见真菌感染。 治疗包括外科切除和长期抗真菌治疗。 一个2.5岁的男孩，患有腹痛，发热和腹泻的10天历史，并检测到可触及的腹部肿块。 切除和组织学证实基础毒性霉菌病。 开始用两性霉素B和Itraconazole治疗，但感染进展并扩散，以涉及肠道，肝，肋骨和肺，以及6个月后的腹壁，需要采用操作程序。 由于对两性霉素和伊丙胺蛋白的反应性，加入口服碘化钾，导致感染完全分辨。 碘化钾是系统性B. ranarum治疗的必要组分。

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