...
首页> 外文期刊>Pediatric allergy, immunology, and pulmonology >Early Stage Impacts of Adenoidectomy With/Without Tonsillectomy on Immune Functions of Children aged <3 Years
【24h】

Early Stage Impacts of Adenoidectomy With/Without Tonsillectomy on Immune Functions of Children aged <3 Years

机译:腺体切除术与/没有扁桃体切除术对3年儿童免疫功能的早期影响

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       

摘要

Objective: To evaluate the early stage effects of adenoidectomy with/without tonsillectomy on immune functions in children aged Methods: Twenty-four children aged <3 years underwent adenoidectomy with/without tonsillectomy were included. The levels of IgG, IgA, IgM, C3, and C4 were measured for humoral immunity, and the levels of CD3(+), CD4(+), CD8(+), CD19(+), CD56(+), CD3(+)CD4(-)CD8(-), and CD3(+)CD4(+)CD8(+) T cells were measured for cellular immunity before and 2 weeks after the operation. Results: The postoperative levels of IgA, IgG, IgM, C3, and C4 were significantly increased compared with the preoperative levels (P < 0.05). The levels of CD3(+), CD4(+), CD8(+), CD56(+), CD3(+)CD4(-)CD8(-), and CD3(+)CD4(+)CD8(+) T cells were increased, while the level of CD19(+) was decreased in postoperative period compared with preoperative period. Compared with those in the control group, the preoperative levels of IgA, IgG, and CD3(+)CD4(+)CD8(+) T cells were significantly increased (P < 0.05), while the levels of IgM, C3, C4 and CD3(+), CD4(+), CD8(+), CD56(+), and CD3(+)CD4(-)CD8(-) T cells were not significantly changed. The postoperative levels of IgA, IgG, C3, C4, CD3(+)CD4(-)CD8(-), and CD3(+)CD4(+)CD8(+) T cells were significantly increased (P < 0.05), while the levels of IgM, CD3(+), CD4(+), CD8(+), and CD56(+) T cells were not significantly changed compared with those in the control group. Conclusion: Adenoidectomy with/without tonsillectomy could stimulate the immune responses, which could avoid significant immune deficiency in a short period of time in children aged <3 years.
机译:目的:评价腺体切除术的早期阶段效应/不含扁桃体切除术治疗儿童免疫功能的方法:包括24岁儿童<3年的腺体切除术治疗腺体切除术。测量IgG,IgA,IgM,C3和C4的水平,用于体液免疫,CD3(+),CD4(+),CD8(+),CD19(+),CD56(+),CD3( +)CD4( - )CD8( - )和CD3(+)CD4(+)CD8(+)C CD8(+)T细胞在手术前2周之前测量细胞免疫力。结果:与术前水平相比,IgA,IgG,IgM,C3和C4的术后水平显着增加(P <0.05)。 CD3(+),CD4(+),CD8(+),CD56(+),CD3(+)CD4( - )CD8( - )和CD3(+)CD4(+)CD8(+)T的水平细胞增加,而术后期间术后期间的CD19(+)水平降低。与对照组中的那些相比,IgA,IgG和CD3(+)CD4(+)CD8(+)T细胞的术前水平显着增加(P <0.05),而IgM,C3,C4和CD3(+),CD4(+),CD8(+),CD56(+)和CD3(+)CD4( - )CD8( - )T细胞没有显着变化。 IgA,IgG,C3,C4,CD3(+)CD4( - )CD8( - )和CD3(+)CD4(+)CD8(+)T细胞的术后水平显着增加(P <0.05),而与对照组中的那些相比,IgM,CD3(+),CD4(+),CD8(+)和CD56(+)T细胞的水平没有显着变化。结论:腺体切除术可以刺激免疫应答,避免在<3年龄的儿童短时间内的显着免疫缺陷。

著录项

  • 来源
  • 作者单位

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

    Hebei Med Univ Childrens Hosp Hebei Prov Shijiazhuang 050030 Hebei Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 儿科学;
  • 关键词

    adenoidectomy; tonsillectomy; humoral immunity; cellular immunity;

    机译:腺体切除术;TonsilleCectomy;体液免疫;细胞免疫;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号