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首页> 外文期刊>Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies >Mechanical Ventilation for Children With Hypoxemic Respiratory Failure After Stem Cell Transplantation: Quo Vadis?
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Mechanical Ventilation for Children With Hypoxemic Respiratory Failure After Stem Cell Transplantation: Quo Vadis?

机译：干细胞移植后患有缺氧呼吸衰竭的儿童的机械通气：QUO VADIS？

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摘要

Over the last 40 years, adults and children with severe life-threatening hypoxemic respiratory failure who receive mechanical ventilation in ICUs continue to have improved short- and long-term survival with mortality decreased from over 60% to under 30%. In 1981, Lyrene and Truog described 60% mortality in children with adult respiratory distress syndrome (ARDS); two of six survivors had severe neurologic problems. A recent systematic review of children with ARDS showed a pooled mortality of 34% and noted that the mortality had not altered over the last 20 years; children with comorbidities such as sepsis, immunosuppression or cancer did worse, as did children with indirect lung injury. Importantly, there were substantial regional and geographical differences. Similarly, a Brazilian study showed a 43% mortality in children with ARDS
机译：在过去的40年中，危及危及生命危及生命的缺氧呼吸衰竭的成人和儿童在ICU中继续改善的短期和长期存活，死亡率从60％下降到30％以下。 1981年，Lyrene和Truog在成人呼吸窘迫综合征（ARDS）中描述了60％的儿童死亡率; 六个幸存者中有两种具有严重的神经系统问题。 最近对有ARD的儿童的系统评价显示出34％的汇集死亡率，并指出，过去20年来死亡率没有改变; 败血症，免疫抑制或癌症等患有血症的儿童确实更糟糕，并且与间接肺损伤的儿童一样。 重要的是，有大量的区域和地理差异。 同样，巴西研究表明，ARDS的儿童患有43％的死亡率

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