...
首页> 外文期刊>Pediatric diabetes. >Closed loop control in adolescents and children during winter sports: Use of the Tandem Control‐IQ AP system
【24h】

Closed loop control in adolescents and children during winter sports: Use of the Tandem Control‐IQ AP system

机译:冬季运动期间青少年和儿童闭环控制:使用串联控制IQ系统

获取原文
获取原文并翻译 | 示例
           

摘要

Abstract Objective Artificial pancreas (AP) systems have been shown to improve glycemic control throughout the day and night in adults, adolescents, and children. However, AP testing remains limited during intense and prolonged exercise in adolescents and children. We present the performance of the Tandem Control‐IQ AP system in adolescents and children during a winter ski camp study, where high altitude, low temperature, prolonged intense activity, and stress challenged glycemic control. Methods In a randomized controlled trial, 24 adolescents (ages 13‐18 years) and 24 school‐aged children (6‐12 years) with Type 1 diabetes (T1D) participated in a 48?hours ski camp (~5 hours skiing/day) at three sites: Wintergreen, VA; Kirkwood, and Breckenridge, CO. Study participants were randomized 1:1 at each site. The control group used remote monitored sensor‐augmented pump (RM‐SAP), and the experimental group used the t: slim X2 with Control‐IQ Technology AP system. All subjects were remotely monitored 24?hours per day by study staff. Results The Control‐IQ system improved percent time within range (70‐180?mg/dL) over the entire camp duration: 66.4 ±?16.4 vs 53.9 ±?24.8%; P =?.01 in both children and adolescents. The AP system was associated with a significantly lower average glucose based on continuous glucose monitor data: 161?±?29.9 vs 176.8 ± 36.5 mg/dL; P =?.023. There were no differences between groups for hypoglycemia exposure or carbohydrate interventions. There were no adverse events. Conclusions The use of the Control‐IQ AP improved glycemic control and safely reduced exposure to hyperglycemia relative to RM‐SAP in pediatric patients with T1D during prolonged intensive winter sport activities.
机译:摘要目的人工胰腺(AP)系统已被证明在成人,青少年和儿童中全天晚上改善血糖控制。然而,AP测试在青少年和儿童的激烈和长时间运动中仍然有限。我们在冬季滑雪营学习期间展示了串联控制-IQ AP系统在青少年和儿童中的表现,高海拔,低温,长期强烈活动和压力挑战血糖控制。在随机对照试验中的方法,24名青少年(13-18岁)和24名学龄儿童(6-12岁),1型糖尿病(T1D)参加了48个小时的滑雪营(〜5小时的滑雪/日)在三个地点:冬青,va; Kirkwood和Breckenridge,Co。学习参与者在每个网站上随机1:1。控制组使用远程监控的传感器增强泵(RM-SAP),实验组使用T:Slim X2与Control IQ技术AP系统。所有受试者通过研究人员每天24小时次要监测。结果控制-IQ系统在整个CANC持续时间内(70-180?mg / dl)的时间百分比提高:66.4±16.4 Vs 53.9±24.8%; P = 01在儿童和青少年中。 AP系统与基于连续葡萄糖监测数据的显着更低的平均血糖有关:161?±29.9 Vs 176.8±36.5 mg / dl; p = 023。低血糖暴露或碳水化合物干预群之间没有差异。没有不良事件。结论使用对照-IQ AP的使用改善了血糖控制,并在长期密集的冬季体育活动期间对T1D的儿科患者RM-SAP安全地降低了高血糖症。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号