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Sexually Transmitted Infections in Pregnant Women: Integrating Screening and Treatment into Prenatal Care

机译：孕妇性传播感染：将筛查和治疗整合到产前护理中

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摘要

Chlamydia, gonorrhea, and syphilis continue to be significant burdens to the health of pregnant women and their children despite easy and effective guidance for screening and treatment. Specific guidelines exist for screening for these infections as well as treatment and follow-up. In this article, we review the epidemiology of chlamydia, gonorrhea, and syphilis. Testing methodology is also reviewed as molecular-based techniques have replaced culture as the current gold standard tests of choice for chlamydia and gonorrhea. The nontreponemal and treponemal serologic diagnostic and screening approach to syphilis has undergone less change. Treatment for gonorrhea includes a one-time dose of parenteral ceftriaxone and oral azithromycin. This treatment regimen not only addresses the possible gonococcal resistance seen in recent years but also treats chlamydia, which may present similarly or co-infect the same patient. Syphilis treatment in both pregnant women and their infected neonates remains with penicillin G formulations. It is crucial to establish close follow-up evaluation for the pregnant woman infected with these sexually transmitted infections to ensure adequate treatment and help prevent perinatal spread of the infection.
机译：尽管容易有效地指导筛查和治疗，但衣原体，淋病和梅毒和梅毒与孕妇及其儿童的健康状况不大。存在筛选这些感染以及治疗和随访的具体指导。在本文中，我们审查了衣原体，淋病和梅毒的流行病学。测试方法也被认为是基于分子的技术已经取代了文化作为衣原体和淋病的当前黄金标准试验。梅毒的非遗传和胸腔血晶诊断和筛选方法经历了更大的变化。用于淋病的治疗包括一次性剂量的肠胃外肠道和口服氮霉素。这种治疗方案不仅涉及近年来可能所见的淋菌性能抗性，而且还可以治疗衣原体，其可能与同一患者类似或共同感染。孕妇和他们感染的新生儿的梅毒治疗仍然是青霉素G配方。为孕妇的密切跟进评估对于感染这些性传播感染的孕妇来确保充分治疗并有助于预防感染的围产期蔓延至关重要。

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  • 来源
    《Pediatric drugs》 |2018年第6期|共9页
  • 作者

    Lochner Harold J. III; Maraqa Nizar F.;

  • 作者单位

    Univ Florida Pediat Infect Dis Coll Med Jacksonville 841 Prudential Dr Suite 1130 Jacksonville;

    Univ Florida Pediat Infect Dis Coll Med Jacksonville 841 Prudential Dr Suite 1130 Jacksonville;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 药学;
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