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首页> 外文期刊>Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation >The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors
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The impact of HIV status, HIV disease progression, and post-traumatic stress symptoms on the health-related quality of life of Rwandan women genocide survivors

机译：HIV状态，艾滋病毒疾病进展和创伤后应激症状对卢旺达妇女种族灭绝幸存者的健康相关质量的影响

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Purpose: We examined whether established associations between HIV disease and HIV disease progression on worse health-related quality of life (HQOL) were applicable to women with severe trauma histories, in this case Rwandan women genocide survivors, the majority of whom were HIV-infected. Additionally, this study attempted to clarify whether post-traumatic stress symptoms were uniquely associated with HQOL or confounded with depression. Methods: The Rwandan Women's Interassociation Study and Assessment was a longitudinal prospective study of HIV-infected and uninfected women. At study entry, 922 women (705 HIV+ and 217 HIV-) completed measures of symptoms of post-traumatic stress and HQOL as well as other demographic, clinical, and behavioral characteristics. Results: Even after controlling for potential confounders and mediators, HIV+ women, in particular those with the lowest CD4 counts, scored significantly worse on HQOL and overall quality of life (QOL) than did HIV- women. Even after controlling for depression and HIV disease progression, women with more post-traumatic stress symptoms scored worse on HQOL and overall QOL than women with fewer post-traumatic stress symptoms. Conclusions: This study demonstrated that post-traumatic stress symptoms were independently associated with HQOL and overall QOL, independent of depression and other confounders or potential mediators. Future research should examine whether the long-term impact of treatment on physical and psychological symptoms of HIV and post-traumatic stress symptoms would generate improvement in HQOL.
机译：目的：我们检查了艾滋病毒疾病和艾滋病毒疾病疾病的进展是否有关较差的健康相关的生命质量（HQOL）是适用于严重创伤史的妇女，在这种情况下，卢旺达妇女种族灭绝幸存者，其中大多数是艾滋病毒感染的。此外，该研究试图阐明创伤后应激症状是否与HQOL相关或混淆抑郁症。方法：卢旺达妇女的渡化研究和评估是对艾滋病毒感染和未感染的妇女的纵向前瞻性研究。在学习进入，922名女性（705艾滋病毒+和217名HIV-）完成了创伤后应力和HQOL症状的症状以及其他人口统计，临床和行为特征。结果：即使在控制潜在的混乱和介质后，艾滋病毒+妇女，特别是CD4计数最低的妇女，对HQOL和整体生活质量（QOL）的均明显越来越差而不是艾滋病毒。即使在控制抑郁症和艾滋病毒疾病的进展后，患有更多创伤后的患者的女性也比具有较少创伤后应激症状的女性更差。结论：本研究表明，创伤后应力症状与HQOL和整体QOL独立相关，与抑郁和其他混乱或潜在的介质无关。未来的研究应检查治疗对艾滋病毒和创伤后应激症状的身心症状的长期影响是否会产生改善的HQOL。

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