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Management of Nonsteroidal Anti-inflammatory Drug-Induced Hypersensitivity Reactions

机译:非甾体抗炎药物诱导的超敏反应的管理

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摘要

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used analgesic, anti-inflammatory, and antipyretic medications on the market. There are currently more than 15 different forms of NSAIDs commercially available in the United States, and they are available as both prescription and OTC drugs. Despite the fact that they are often consumed daily, their use comes with a broad variety of adverse effects ranging from gastrointestinal irritation to severe, life-threatening anaphy-laxis. NS AID-induced hypersensitivity reactions (NHRs) have been reported in about 0.3% to 6% of the general population and are thought to account for 20% to 30% of all drug-related reactions, placing them second behind antibiotic-associated hypersensitivity reactions.
机译:非甾体类抗炎药(NSAID)是市场上最常用的镇痛,抗炎和和解热药物之一。 目前有超过15种不同形式的NSAID,在美国可商购获得,它们可作为处方和OTC药物提供。 尽管它们经常每天消耗,但它们的用途具有广泛的胃肠刺激对严重,生命威胁的胃肠狂欢的各种不利影响。 据报道,NS辅助诱导的超敏反应(NHRS)约为一般人群的0.3%至6%,并被认为占所有药物相关反应的20%至30%,将其占抗生素相关的过敏反应的第二次 。

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