Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome

Bhatt Ravi R.; Gupta Arpana; Labus Jennifer S.; Zeltzer Lonnie K.; Tsao Jennie C.; Shulman Robert J.; Tillisch Kirsten

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Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome

机译：改变的脑结构和功能连接及其与肠易激综合征女孩疼痛感知的关系

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Objective Imaging studies in adults with irritable bowel syndrome (IBS) have shown both morphological and resting state (RS) functional connectivity (FC) alterations related to cortical modulation of sensory processing. Because analogous differences have not been adequately investigated in children, this study compared gray matter volume (GMV) and RS-FC between girls with IBS and healthy controls (HC) and tested the correlation between brain metrics and laboratory-based pain thresholds (Pth).

机译：具有肠肠综合征（IBS）的成人的客观成像研究表明了与感官加工的皮质调制相关的形态和休息状态（RS）功能连通性（FC）改变。因为在儿童中没有被充分调查类似的差异，但该研究比较了IBS和健康对照（HC）的女孩之间的灰质体积（GMV）和RS-Fc，并测试了脑度量和实验室疼痛阈值之间的相关性（PTH）。

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来源
《Psychosomatic Medicine: Journal of the American Psychosomatic Society》 |2019年第2期|共9页
作者
Bhatt Ravi R.; Gupta Arpana; Labus Jennifer S.; Zeltzer Lonnie K.; Tsao Jennie C.; Shulman Robert J.; Tillisch Kirsten;
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作者单位

Univ Calif Los Angeles Dept Pediat Pediat Pain &

Palliat Care Program Los Angeles CA 90024 USA;

Univ Calif Los Angeles David Geffen Sch Med Los Angeles CA 90095 USA;

Univ Calif Los Angeles David Geffen Sch Med Los Angeles CA 90095 USA;

Univ Calif Los Angeles Dept Pediat Pediat Pain &

Palliat Care Program Los Angeles CA 90024 USA;

Univ Calif Los Angeles Dept Pediat Pediat Pain &

Palliat Care Program Los Angeles CA 90024 USA;

Baylor Coll Med Dept Pediat Childrens Nutr Res Ctr Houston TX 77030 USA;

Univ Calif Los Angeles David Geffen Sch Med Los Angeles CA 90095 USA;

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原文格式 PDF
正文语种 eng
中图分类医学心理学、病理心理学;
关键词
children with irritable bowel syndrome; cortical modulation; functional and structural MRI; pain sensitivity; sensory processing;

机译：肠综合征肠辨别的儿童;皮质调制;功能性和结构MRI;疼痛敏感性;感官加工;

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1. Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome [J] . Bhatt Ravi R., Gupta Arpana, Labus Jennifer S., Psychosomatic Medicine: Journal of the American Psychosomatic Society . 2019,第2期

机译：改变的脑结构和功能连接及其与肠易激综合征女孩疼痛感知的关系
2. Irritable bowel syndrome and bladder pain syndrome comorbidities are associated with altered quality of life, anxiety, depression and sleep in patients with functional dyspepsia [J] . Neurogastroenterology and motility . 2019,第S4期

机译：肠易肠综合征和膀胱疼痛综合征的合并症与功能性消化不良患者的生活质量，焦虑，抑郁和睡眠改变有关
3. Altered brain spontaneous activity and connectivity network in irritable bowel syndrome patients: A resting-state fMRI study [J] . Ma Xiaofen, Li Shumei, Tian Junzhang, Clinical neurophysiology . 2015,第6期

机译：肠易激综合征患者的大脑自发活动和连接网络改变：静态fMRI研究
4. State-of-the Art Lecture: Irritable bowel syndrome: the new inflammatory bowel disease? [C] . R. C. SPILLE Falk Symposium . 2006

机译：最先进的讲座：肠易激综合征：新的炎症性肠病？
5. Structural and Functional Brain Alterations in Patients with Irritable Bowel Syndrome [D] . Hong, Jui-Yang 2015

机译：肠易激综合征患者的结构和功能性大脑改变
6. Does Acupuncture Therapy Alter Activation of Neural Pathway for Pain Perception in Irritable Bowel Syndrome?: A Comparative Study of True and Sham Acupuncture Using Functional Magnetic Resonance Imaging [O] . Winnie CW Chu, Justin CY Wu, David TW Yew, 2012

机译：针灸疗法会改变肠易激综合征疼痛知觉的神经通路激活吗？：使用功能磁共振成像对真假针刺和假针刺的比较研究
7. Does Acupuncture Therapy Alter Activation of Neural Pathway for Pain Perception in Irritable Bowel Syndrome?: A Comparative Study of True and Sham Acupuncture Using Functional Magnetic Resonance Imaging [O] . 2015

机译：针灸治疗改变肠易激综合征疼痛的神经通路激活作用 - 真实与假针刺功能磁共振成像的对比研究

Altered Brain Structure and Functional Connectivity and Its Relation to Pain Perception in Girls With Irritable Bowel Syndrome

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