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Quality of Life and Psychosocial Functioning 2 Years Following Facial Transplantation

机译：面部移植后2年的生活质量和心理社会功能

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Background: Face transplantation is a novel option for patients with severe facial disfigurement. Quality of life (QoL) outcomes of face transplantation remain poorly understood. Objectives: We sought to evaluate psychosocial functioning among 6 patients undergoing facial transplantation. Methods: We prospectively assessed depressive symptoms, health status, mental and physical QoL, and self-esteem at 3-month intervals for 2 years. Social desirability was assessed pretransplant. Results: On average, before transplantation, patients generally reported minimal to subthreshold depressive symptoms, normal to high health status, normal mental-health QoL, slightly below normal physical-health QoL, and normal to high self-esteem. Most endorsed high social desirability. As patients recovered from surgery, hospitalization, and immunosuppression induction, physical-health QoL generally deteriorated 3 months posttransplantation. Posttransplant trajectories show that perceived health state improved; health status and mental and physical health-related QoL slightly improved; self-esteem remained stable and high; and overall depressive symptoms remained stable but 3 patients experienced a depressive episode. Conclusions: Pretransplant ceiling effects may render improvements difficult to quantify. Future research should use mixed methods including population-specific measures with demonstrated sensitivity to change.
机译：背景：面部移植是一种严重面部毁伤患者的新选择。人的生活质量（QOL）脸部移植的结果仍然明白。目的：我们试图评估6名接受面部移植的患者的心理社会功能。方法：我们预期评估抑郁症状，健康状况，心理和物理QOL，以及3个月间隔的自尊2年。评估人们的预持久性。结果：平均，移植前，患者普遍认为亚阈值抑郁症状最小，正常到高健康状况，正常心理健康QOL，略低于正常的身体健康QOL，对高度正常的尊重。最高的社会责任。随着患者从手术，住院治疗和免疫抑制诱导中恢复，身体健康QOL通常会导致3个月后持续。 PostAlsplant轨迹表明感知健康状态改善;健康状况和精神和身体健康相关的QOL略微改善;自尊保持稳定和高;整体抑郁症状保持稳定，但3名患者经历了抑郁症。结论：预防植物的天花板效应可能使改善难以量化。未来的研究应该使用混合方法，包括人口特定措施，表现出对变革的敏感性。

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