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首页> 外文期刊>Psychosomatics >Reduced Anxiety and Depression in Patients With Advanced Heart Failure After Left Ventricular Assist Device Implantation
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Reduced Anxiety and Depression in Patients With Advanced Heart Failure After Left Ventricular Assist Device Implantation

机译：左心室辅助装置植入后晚期心力衰竭患者减少焦虑和抑郁症

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Background: Despite the high prevalence of depression and anxiety in patients with advanced heart failure, the effects of left ventricular assist device (LVAD) implantation on these critically important aspects of mental health are not well understood. Objective: We sought to assess changes in depression and anxiety following LVAD implantation. Methods: The Beck Depression Inventory-II (BDI-II) and Beck Anxiety Inventory (BAI) were administered to 54 patients by a clinical psychologist at a mean of 12 days before LVAD implantation and 251 days after implantation. Patient demographics and clinical data were collected concurrently to psychologic testing. Changes in BDI-II, BAI, and clinical markers of heart failure were assessed using paired t-tests. A p < 0.05 was considered significant. Results: The average age of the group was 56.63 years with a mean ejection fraction 20.8%. Before implantation, mean BAI and BDI scores indicated mild depression and anxiety. Following LVAD implantation, average scores for both BDI-II and BAI decreased significantly, indicating minimal depression and anxiety (12.6-8.54, p = 0.001 and 12.06-6.6, p < 0.001, respectively). Mean scores were significantly lowered in 11 and 8 of the 21 subdomains tested by the BAI and BDI, respectively. Significant improvements were noted in post-LVAD B-type natriuretic peptide, serum sodium, and blood urea nitrogen. Conclusion: Depression and anxiety scores improved significantly after LVAD implantation. Factors contributing to changes in depression and anxiety after LVAD could be related to the improvement in acute heart failure sy.mptoms, functional capacity, and quality of life. Prospective studies with larger sample sizes are warranted.
机译：背景：尽管心力衰竭患者的抑郁和焦虑患病率高，但左心室辅助装置（LVAD）植入对心理健康的这些批判性重要方面的影响尚不清楚。目的：我们试图评估LVAD植入后抑郁和焦虑的变化。方法：临床心理学家患有12天，在LVAD植入前12天和植入前251天，将Beck抑郁症II-II（BDI-II）和Beck焦虑库存（BAI）施用至54名患者。患者人口统计和临床数据同时收集到心理学测试。使用配对的T检验评估BDI-II，Bai，Bai和心力衰竭临床标志物的变化。 P <0.05被认为是显着的。结果：本集团的平均年龄为56.63岁，平均喷射分数20.8％。在植入前，平均白和BDI分数表明轻度抑郁和焦虑。在LVAD植入之后，BDI-II和Bai的平均评分显着下降，表明最小的抑郁和焦虑（12.6-8.54，P = 0.001和12.06-6.6，P <0.001）。在白和BDI测试的21个亚域的11和8中，平均分子显着降低。后LVAD B型利钠肽，血清钠和血尿尿素氮，注意到显着改善。结论：LVAD植入后抑郁和焦虑分数显着提高。在LVAD后抑郁和焦虑变化的因素可能与急性心力衰竭的改善有关。有必要进行更大样本尺寸的前瞻性研究。

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