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首页> 外文期刊>Psychosomatics >Feeding Systems and the Gut Microbiome: Gut-Brain Interactions With Relevance to Psychiatric Conditions
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Feeding Systems and the Gut Microbiome: Gut-Brain Interactions With Relevance to Psychiatric Conditions

机译：饲养系统和肠道微生物组：肠脑与精神疾病相关的相互作用

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Background Physical and mental health is dependent on the environment, and feeding is a prime example of this environmental exchange. While the hypothalamus controls both feeding behavior and the stress response, the integration of the neural control centers and the peripheral gut allows for disruption in the gastrointestinal systems and dysfunctional communication to the brain. Objective The purpose of this review is to familiarize clinicians with the physiology controlling feeding behavior and its implications for psychiatric conditions, such as anorexia nervosa and depression. Growing understanding of how integrated bacterial life is in the body has shown that gut bacteria regulate basic physiologic processes and are implicated in various disease states and contribute to regulation of mood. Responses to stress have effects on feeding behavior and mood and the regulation of the stress response by the gut microbiota could contribute to the dysfunction seen in patients with psychiatric illnesses. Conclusions Gut microbiota may contribute to dysfunction in psychiatric illnesses. New opportunities to modulate existing gut microbiota using probiotics could be novel targets for clinical interventions.
机译：背景技术身心健康依赖于环境，饲料是这种环境交流的主要例子。虽然下丘脑控制喂养行为和应力响应，但神经控制中心和周边肠道的整合允许在胃肠系统中破坏和与大脑的功能失调通信。目的本综述的目的是熟悉临床医生，临床医生控制饲养行为的生理学和其对精神病病症的影响，例如厌食症和抑郁症。越来越多地了解综合细菌生活如何在体内已经表明，肠道细菌调节基本的生理过程，并涉及各种疾病状态并有助于调节情绪。对压力的反应对饲养行为和情绪的影响以及肠道微生物的应力反应的调节可能有助于精神疾病患者的功能障碍。结论肠道微生物会可能有助于心理疾病功能障碍。使用益生菌调节现有肠道微生物群的新机会可能是临床干预措施的新靶点。

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