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首页> 外文期刊>Urolithiasis. >Transient renal impairment in the absence of pre-existing chronic kidney disease in patients with unilateral ureteric stone impaction
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Transient renal impairment in the absence of pre-existing chronic kidney disease in patients with unilateral ureteric stone impaction

机译：在单侧输尿管石块患者患者中缺乏患者患者缺乏肾病障碍

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摘要

This study aims to describe the rate and characteristics of transient renal impairment in unilateral ureteric stone patients without chronic kidney disease (CKD) and to identify factors that may have influenced renal function of these patients. Unilateral ureteric stone patients who visited our hospital's emergency department from December, 2009 to December, 2015 were divided into two groups based on estimated glomerular filtration rate (eGFR): group I (patients with eGFR ae 60 ml/min/1.73 m(2)) and group II (eGFR < 60 ml/min/1.73 m(2)). A univariate comparison between groups I and II was performed. Multivariable logistic regression analysis was performed to determine factors that influenced renal function. There were 107 patients in group II, which constituted 5.6 % of the total patients. In the multivariable logistic regression analysis, age (p < 0.001, odds ratio [OR] = 1.069, confidence interval [CI] = 1.049-1.089), hypertension (p < 0.001, OR = 2.302, CI = 1.467-3.611), stone size (p = 0.001, OR = 1.141, CI = 1.057-1.231), white blood cell count (p = 0.001, OR = 1.132, CI = 1.055-1.215) and hematuria (p < 0.001, OR = 0.383, CI = 0.231-0.636) were found to be independent factors for renal impairment. Based on the results of this study, the rate of renal impairment was 6 % of the unilateral ureteric stone patients without pre-existing CKD. Age and hypertension were found to be independent factors for renal impairment; NSAIDs should be used cautiously or other agents for pain relief such as opioids should be considered in old aged patients with hypertension.
机译：本研究旨在描述单方面输尿管石患者的瞬态肾损伤的速率和特征，没有慢性肾病（CKD），并确定可能影响这些患者肾功能的因素。从2009年12月到2015年12月访问我们医院的急诊部门的单侧输尿管石患者分为两组，基于估计的肾小球过滤率（EGFR）：I组（EGFR AE 60 ml / min / 1.73米（2）患者）和II族（EGFR <60ml / min / 1.73m（2））。执行一组和II组之间的​​单变量比较。进行多变量逻辑回归分析以确定影响肾功能的因素。 II组中有107名患者，占患者的5.6％。在多变量逻辑回归分析中，年龄（P <0.001，差距[或] = 1.069，置信区间[CI] = 1.049-1.089），高血压（P <0.001，或= 2.302，CI = 1.467-3.611），石头尺寸（p = 0.001，或= 1.141，CI = 1.057-1.231），白细胞计数（p = 0.001，或= 1.132，CI = 1.055-1.215）和血尿（P <0.001，或= 0.383，CI = 0.231 - 0.636）被发现是肾脏损伤的独立因素。根据本研究的结果，肾脏损伤率为6％，无需预先存在的CKD。年龄和高血压被发现是肾脏损伤的独立因素; NSAIDS应谨慎使用或其他药物用于疼痛缓解，例如阿片类药物的高血压患者应考虑。

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