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A preliminary survey of practice patterns across several European kidney stone centers and a call for action in developing shared practice

机译:几个欧洲肾结石中心实践模式的初步调查,并在开发共享实践中的行动呼吁

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Currently an evidence-based approach to nephrolithiasis is hampered by a lack of randomized controlled trials. Thus, there is a need for common platforms for data sharing and recruitment of patients to interventional studies. A first step in achieving this objective would be to share practice methods and protocols for subsequent standardization in what is still a heterogeneous clinical field. Here, we present the results of a pilot survey performed across 24 European clinical kidney stone centers. The survey was distributed by a voluntary online questionnaire circulated between June 2017 and January 2018. About 46% of centers reported seeing on average 20 or more patients per month. Only 21% adopted any formal referral criteria. Centers were relatively heterogeneous in respect of the definition of an incident stone event. The majority (71%) adopted a formal follow-up scheme; of these, 65% included a follow-up visit at 3 and 12 months, and 41% more than 12 months. In 79% of centers some kind of imaging was performed systematically. 75% of all centers performed laboratory analyses on blood samples at baseline and during follow-up. All centers performed laboratory analyses on 24-h urine samples, the majority (96%) at baseline and during follow-up. There was good correspondence across centers for analyses performed on 24-h urine samples, although the methods of 24-h urine collection and analysis were relatively heterogeneous. Our survey among 24 European stone centers highlights areas of homogeneity and heterogeneity that will be investigated further. Our aim is the creation of a European network of stone centers sharing practice patterns and hosting a common database for research and guidance in clinical care.
机译:目前,缺乏随机对照试验的基于证据的肾肾病方法受到阻碍。因此,需要对患者的数据共享和招募患者进行介入研究的共同平台。实现这一目标的第一步是分享实践方法和协议,以便随后的标准化在仍然是一种异质临床领域。在这里,我们介绍了在24个欧洲临床肾脏石碑上进行的试验调查结果。该调查由2017年6月至2018年1月至2018年1月分配的自愿在线问卷分发。大约46%的中心报告每月平均看到20例或更多患者。只有21%采用任何正式转诊标准。关于事件石头事件的定义,中心是相对异质的。大多数(71%)通过了正式的后续计划;其中,65%包括3至12个月的后续访问,41%超过12个月。在79%的中心系统地进行了某种成像。 75%的所有中心在基线和随访期间进行了实验室分析了血液样本。所有中心在24小时尿样,大多数(96%)的基线和随访期间进行了实验室分析。对于在24小时尿液样本上进行的分析中心存在良好的对应性,尽管24-H尿液收集和分析的方法相对异质。我们在24个欧洲石碑之间的调查突出了将进一步调查的同质性和异质性领域。我们的宗旨是建立欧洲的石碑网络分享实践模式,并托管临床护理中的研究和指导的共同数据库。

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