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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment
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Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment

机译:治疗10年后奥兰扎滨诱导的神经抑制恶性综合征

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摘要

Neuroleptic malignant syndrome (NMS) is a dangerous, life-threatening condition that can be caused by antip-sychotic drugs (Ananth et al., 2004; Yasugi et al., 2010). Food and Drug Administration (FDA) reports from 1999-2012 indicate that the frequency of NMS decreases when treatment with olanzapine is continued for a longer period (eHealthMe, 2013).According to an eHealthMe report compiled from the FDA reports, 11,204 patients taking olanzapine had suffered adverse effects, of which 417 patients had NMS during the first 6 months of treatment (eHealthMe, 2013). However, so far nobody has recorded a patient who has had NMS in the initial stages of typical neuroleptic treatment and another episode of NMS after 10 years of olanzapine treatment. To our knowledge, this report is the first to record the occurrence of NMS, 10 years after the implementation of olanzapine.
机译:神经抑制的恶性综合征(NMS)是一种危险,危及生命的病症,可能是由抗癫虫药物引起的(Ananth等,2004; Yasugi等,2010)。 1999 - 2012年的食品和药物管理局(FDA)报告表明,当奥兰扎滨的治疗继续进行更长的时间(EHEELTHME,2013)时,NMS的频率降低。根据从FDA报告编制的eHealthme报告,11,204名服用奥兰扎 遭受不良反应,其中417名患者在治疗的前6个月内有NMS(eHealthme,2013)。 然而,到目前为止,没有人记录了患有典型神经抑制治疗的初始阶段的患者,并且在10年后的奥拉扎滨治疗后的另一种NMS发作。 据我们所知,本报告是第一个在奥兰扎滨实施后10年录制NMS的发生。

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